7OOX

Crystal structure of PIM1 in complex with ARC-3126

Summary for 7OOX

• Entry DOI: 10.2210/pdb7oox/pdb
• Related PRD ID: PRD_002346
• Descriptor: Serine/threonine-protein kinase pim-1, Inhibitor ARC-3126, PHOSPHATE ION, ... (5 entities in total)
• Functional Keywords: pim1, inhibitor, kinase, kinase substrate, structural genomics, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 37366.32

Authors

Chaikuad, A.,Dixon-Clarke, S.E.,Nonga, O.E.,Uri, A.,Bullock, A.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2021-05-28, release date: 2021-08-04, Last modification date: 2024-01-31)

• Primary citation: Nonga, O.E.,Lavogina, D.,Enkvist, E.,Kestav, K.,Chaikuad, A.,Dixon-Clarke, S.E.,Bullock, A.N.,Kopanchuk, S.,Ivan, T.,Ekambaram, R.,Viht, K.,Knapp, S.,Uri, A.; Crystal Structure-Guided Design of Bisubstrate Inhibitors and Photoluminescent Probes for Protein Kinases of the PIM Family.; Molecules, 26:-, 2021; PubMed: 34299628; DOI: 10.3390/molecules26144353

Experimental method

X-RAY DIFFRACTION (1.97 Å)