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9HX2
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BU of 9hx2 by Molmil
X-ray crystal structure of PPAR gamma Ligand Binding Domain in complex with CZ58
Descriptor: 2-[3-[(2~{R})-3-(4-bromophenyl)-4-oxidanyl-5-oxidanylidene-2~{H}-furan-2-yl]phenoxy]ethanoic acid, Peroxisome proliferator-activated receptor gamma
Authors:Capelli, D, Montanari, R.
Deposit date:2025-01-06
Release date:2025-05-14
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Enhancing the activity of gamma-hydroxy lactone derivatives as innovative peroxisome proliferator-activated receptor gamma non-agonists inhibiting cyclin-dependent kinase 5-mediated phosphorylation.
Eur.J.Med.Chem., 292, 2025
3OEL
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BU of 3oel by Molmil
Crystal structure of GluN2D ligand-binding core in complex with D-glutamate
Descriptor: D-GLUTAMIC ACID, Glutamate [NMDA] receptor subunit epsilon-4
Authors:Simorowski, N, Furukawa, H.
Deposit date:2010-08-12
Release date:2011-05-11
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors.
Nat Commun, 2, 2011
3OEN
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BU of 3oen by Molmil
Crystal structure of GluN2D ligand-binding core in complex with L-glutamate
Descriptor: GLUTAMIC ACID, Glutamate [NMDA] receptor subunit epsilon-4
Authors:Simorowski, N, Furukawa, H.
Deposit date:2010-08-12
Release date:2011-05-11
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors.
Nat Commun, 2, 2011
3OEK
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BU of 3oek by Molmil
Crystal structure of GluN2D ligand-binding core in complex with L-aspartate
Descriptor: ASPARTIC ACID, Glutamate [NMDA] receptor subunit epsilon-4
Authors:Simorowski, N, Furukawa, H.
Deposit date:2010-08-12
Release date:2011-05-11
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors.
Nat Commun, 2, 2011
6P0A
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BU of 6p0a by Molmil
Human DNA Ligase 1 Bound to an Adenylated, dideoxy Terminated DNA nick with 2 mM Mg2+
Descriptor: ADENOSINE MONOPHOSPHATE, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*C)-3'), DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ...
Authors:Schellenberg, M.J, Williams, R.S, Tumbale, P.S, Riccio, A.A.
Deposit date:2019-05-16
Release date:2019-12-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Two-tiered enforcement of high-fidelity DNA ligation.
Nat Commun, 10, 2019
6P0D
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BU of 6p0d by Molmil
Human DNA Ligase 1 (E346A/E592A) Bound to an Adenylated, hydroxyl terminated DNA nick
Descriptor: ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*C)-3'), ...
Authors:Schellenberg, M.J, Williams, R.S, Tumbale, P.S, Riccio, A.A.
Deposit date:2019-05-16
Release date:2019-12-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Two-tiered enforcement of high-fidelity DNA ligation.
Nat Commun, 10, 2019
6P0C
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BU of 6p0c by Molmil
Human DNA Ligase 1 Bound to an Adenylated, hydroxyl terminated DNA nick in EDTA
Descriptor: ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*C)-3'), ...
Authors:Schellenberg, M.J, Tumbale, P.S, Riccio, A.A, Williams, R.S.
Deposit date:2019-05-16
Release date:2019-12-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Two-tiered enforcement of high-fidelity DNA ligation.
Nat Commun, 10, 2019
2ZBS
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BU of 2zbs by Molmil
Crystal structure of human estrogen-related receptor gamma ligand binding domain apo form
Descriptor: Estrogen-related receptor gamma
Authors:Matsushima, A, Kakuta, Y, Teramoto, T, Shimohigashi, Y.
Deposit date:2007-10-27
Release date:2008-10-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:ERRgamma tethers strongly bisphenol A and 4-alpha-cumylphenol in an induced-fit manner
Biochem.Biophys.Res.Commun., 373, 2008
6P09
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BU of 6p09 by Molmil
Human DNA Ligase 1 Bound to an Adenylated, dideoxy Terminated DNA nick with 200 mM Mg2+
Descriptor: ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*C)-3'), ...
Authors:Schellenberg, M.J, Williams, R.S, Tumbale, P.S, Riccio, A.A.
Deposit date:2019-05-16
Release date:2019-12-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.052 Å)
Cite:Two-tiered enforcement of high-fidelity DNA ligation.
Nat Commun, 10, 2019
6P0E
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BU of 6p0e by Molmil
Human DNA Ligase 1 (E346A,E592A) bound to adenylated DNA containing an 8-oxo guanine:adenine base-pair
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
Authors:Schellenberg, M.J, Williams, R.S, Tumbale, P.S, Riccio, A.A.
Deposit date:2019-05-16
Release date:2019-12-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Two-tiered enforcement of high-fidelity DNA ligation.
Nat Commun, 10, 2019
6LW8
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BU of 6lw8 by Molmil
Structural basis for domain rotation during adenylation of active site K123 and fragment library screening against NAD+ -dependent DNA ligase from Mycobacterium tuberculosis
Descriptor: (4R)-4-(4-fluorophenyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine, DNA ligase A, GLYCEROL, ...
Authors:Ramachandran, R, Afsar, M, Shukla, A.
Deposit date:2020-02-07
Release date:2021-02-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Structure based identification of first-in-class fragment inhibitors that target the NMN pocket of M. tuberculosis NAD + -dependent DNA ligase A.
J.Struct.Biol., 213, 2021
8C0C
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BU of 8c0c by Molmil
X-ray crystal structure of PPAR gamma ligand binding domain in complex with CZ46
Descriptor: (2~{R})-2-[4-(naphthalen-1-ylmethoxy)phenyl]-4-oxidanyl-3-phenyl-2~{H}-furan-5-one, Peroxisome proliferator-activated receptor gamma
Authors:Capelli, D, Montanari, R, Pochetti, G, Villa, S, Meneghetti, F.
Deposit date:2022-12-16
Release date:2023-04-26
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Biological Screening and Crystallographic Studies of Hydroxy gamma-Lactone Derivatives to Investigate PPAR gamma Phosphorylation Inhibition.
Biomolecules, 13, 2023
6Q1V
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BU of 6q1v by Molmil
Human DNA Ligase 1 (E592R) Bound to an Adenylated, hydroxyl terminated DNA nick
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ADENOSINE MONOPHOSPHATE, ...
Authors:Schellenberg, M.J, Williams, R.S, Tumbale, P.S, Riccio, A.A.
Deposit date:2019-08-06
Release date:2019-12-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Two-tiered enforcement of high-fidelity DNA ligation.
Nat Commun, 10, 2019
6SSP
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BU of 6ssp by Molmil
Structure of the pentameric ligand-gated ion channel ELIC in complex with a NAM nanobody
Descriptor: CALCIUM ION, Cys-loop ligand-gated ion channel, NANOBODY 21, ...
Authors:Ulens, C, Brams, M, Evans, G.L, Spurny, R, Govaerts, C, Pardon, E, Steyaert, J.
Deposit date:2019-09-09
Release date:2020-02-12
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT 3 receptor via a common vestibule site.
Elife, 9, 2020
6P0B
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BU of 6p0b by Molmil
Human DNA Ligase 1 (E346A/E592A) Bound to an Adenylated, dideoxy Terminated DNA nick with 200 mM Mg2+
Descriptor: ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*C)-3'), ...
Authors:Schellenberg, M.J, Williams, R.S, Tumbale, P.S, Riccio, A.A.
Deposit date:2019-05-16
Release date:2019-12-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.203 Å)
Cite:Two-tiered enforcement of high-fidelity DNA ligation.
Nat Commun, 10, 2019
6SSI
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BU of 6ssi by Molmil
Structure of the pentameric ligand-gated ion channel ELIC in complex with a PAM nanobody
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, CALCIUM ION, ...
Authors:Ulens, C, Brams, M, Evans, G.L, Spurny, R, Govaerts, C, Pardon, E, Steyaert, J.
Deposit date:2019-09-07
Release date:2020-02-12
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT 3 receptor via a common vestibule site.
Elife, 9, 2020
3GSL
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BU of 3gsl by Molmil
Crystal structure of PSD-95 tandem PDZ domains 1 and 2
Descriptor: Disks large homolog 4
Authors:Sainlos, M, Olivier, N.B, Imperiali, B.
Deposit date:2009-03-27
Release date:2010-09-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Biomimetic divalent ligands for the acute disruption of synaptic AMPAR stabilization.
Nat.Chem.Biol., 7, 2011
1IOW
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BU of 1iow by Molmil
COMPLEX OF Y216F D-ALA:D-ALA LIGASE WITH ADP AND A PHOSPHORYL PHOSPHINATE
Descriptor: 1(S)-AMINOETHYL-(2-CARBOXYPROPYL)PHOSPHORYL-PHOSPHINIC ACID, ADENOSINE-5'-DIPHOSPHATE, D-ALA:D-ALA LIGASE, ...
Authors:Knox, J.R, Moews, P.C, Fan, C.
Deposit date:1996-09-20
Release date:1997-02-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:D-alanine:D-alanine ligase: phosphonate and phosphinate intermediates with wild type and the Y216F mutant.
Biochemistry, 36, 1997
1T5H
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BU of 1t5h by Molmil
4-Chlorobenzoyl-CoA Ligase/Synthetase unliganded, selenomethionine
Descriptor: 4-chlorobenzoyl CoA ligase, CALCIUM ION
Authors:Gulick, A.M, Lu, X, Dunaway-Mariano, D.
Deposit date:2004-05-04
Release date:2004-08-03
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Crystal Structure of 4-Chlorobenzoate:CoA Ligase/Synthetase in the Unliganded and Aryl Substrate-Bound States
Biochemistry, 43, 2004
7BBR
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BU of 7bbr by Molmil
Crystal structure of the sugar acid binding protein DctPAm from Advenella mimigardefordensis strain DPN7T
Descriptor: 2-KETO-3-DEOXYGLUCONATE, Putative TRAP transporter solute receptor DctP
Authors:Schaefer, L, Meinert, C, Kobus, S, Hoeppner, A, Smits, S.H, Steinbuechel, A.
Deposit date:2020-12-18
Release date:2021-03-24
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of the sugar acid-binding protein CxaP from a TRAP transporter in Advenella mimigardefordensis strain DPN7 T .
Febs J., 288, 2021
7BCP
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BU of 7bcp by Molmil
Crystal structure of the sugar acid binding protein DctPAm from Advenella mimigardefordensis strain DPN7T in complex with gluconate
Descriptor: D-gluconic acid, Putative TRAP transporter solute receptor DctP
Authors:Schaefer, L, Meinert, C, Kobus, S, Hoeppner, A, Smits, S.H, Steinbuechel, A.
Deposit date:2020-12-21
Release date:2021-04-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the sugar acid-binding protein CxaP from a TRAP transporter in Advenella mimigardefordensis strain DPN7 T .
Febs J., 288, 2021
7BCO
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BU of 7bco by Molmil
Crystal structure of the sugar acid binding protein DctPAm from Advenella mimigardefordensis strain DPN7T in complex with D-foconate
Descriptor: (2R,3S,4S,5S)-2,3,4,5-tetrahydroxyhexanoic acid, Putative TRAP transporter solute receptor DctP
Authors:Schaefer, L, Meinert, C, Kobus, S, Hoeppner, A, Smits, S.H, Steinbuechel, A.
Deposit date:2020-12-21
Release date:2021-04-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the sugar acid-binding protein CxaP from a TRAP transporter in Advenella mimigardefordensis strain DPN7 T .
Febs J., 288, 2021
6R7I
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BU of 6r7i by Molmil
Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
Descriptor: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ...
Authors:Faull, S.F, Lau, A.M.C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A.
Deposit date:2019-03-28
Release date:2019-08-28
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.
Nat Commun, 10, 2019
3V5Y
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BU of 3v5y by Molmil
Structure of FBXL5 hemerythrin domain, P2(1) cell
Descriptor: F-box/LRR-repeat protein 5, MU-OXO-DIIRON
Authors:Tomchick, D.R, Bruick, R.K, Thompson, J.W, Brautigam, C.A.
Deposit date:2011-12-17
Release date:2012-01-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Molecular Characterization of Iron-sensing Hemerythrin-like Domain within F-box and Leucine-rich Repeat Protein 5 (FBXL5).
J.Biol.Chem., 287, 2012
3V5X
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BU of 3v5x by Molmil
Structure of FBXL5 hemerythrin domain, C2 cell
Descriptor: F-box/LRR-repeat protein 5, MU-OXO-DIIRON
Authors:Tomchick, D.R, Bruick, R.K, Thompson, J.W, Brautigam, C.A.
Deposit date:2011-12-17
Release date:2012-01-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and Molecular Characterization of Iron-sensing Hemerythrin-like Domain within F-box and Leucine-rich Repeat Protein 5 (FBXL5).
J.Biol.Chem., 287, 2012

238582

数据于2025-07-09公开中

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