6SSI

Structure of the pentameric ligand-gated ion channel ELIC in complex with a PAM nanobody

Summary for 6SSI

• Entry DOI: 10.2210/pdb6ssi/pdb
• Descriptor: Cys-loop ligand-gated ion channel, NANOBODY 22, GAMMA-AMINO-BUTANOIC ACID, ... (10 entities in total)
• Functional Keywords: ion channel, cys-loop receptor, pentameric ligand gated ion channel, lgic, elic, nanobody, transport protein
• Biological source: Dickeya chrysanthemi (Pectobacterium chrysanthemi); More
• Total number of polymer chains: 10
• Total formula weight: 254534.19

Authors

Ulens, C.,Brams, M.,Evans, G.L.,Spurny, R.,Govaerts, C.,Pardon, E.,Steyaert, J. (deposition date: 2019-09-07, release date: 2020-02-12, Last modification date: 2024-01-24)

• Primary citation: Brams, M.,Govaerts, C.,Kambara, K.,Price, K.L.,Spurny, R.,Gharpure, A.,Pardon, E.,Evans, G.L.,Bertrand, D.,Lummis, S.C.,Hibbs, R.E.,Steyaert, J.,Ulens, C.; Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT 3 receptor via a common vestibule site.; Elife, 9:-, 2020; PubMed: 31990273; DOI: 10.7554/eLife.51511

Experimental method

X-RAY DIFFRACTION (2.59 Å)