8WNJ
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![BU of 8wnj by Molmil](/molmil-images/mine/8wnj) | Crystal structure of H. pylori isoleucyl-tRNA synthetase (HpIleRS) in complex with Ile-AMP | Descriptor: | ACETATE ION, GLYCEROL, Isoleucine--tRNA ligase, ... | Authors: | Guo, Y, Li, S, Zhang, T. | Deposit date: | 2023-10-06 | Release date: | 2024-02-14 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structural basis for substrate and antibiotic recognition by Helicobacter pylori isoleucyl-tRNA synthetase. Febs Lett., 598, 2024
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8WNI
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![BU of 8wni by Molmil](/molmil-images/mine/8wni) | Crystal structure of H. pylori isoleucyl-tRNA synthetase (HpIleRS) in complex with Val | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, GLYCEROL, ... | Authors: | Guo, Y, Li, S, Zhang, T. | Deposit date: | 2023-10-06 | Release date: | 2024-02-14 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis for substrate and antibiotic recognition by Helicobacter pylori isoleucyl-tRNA synthetase. Febs Lett., 598, 2024
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8WNH
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8WNG
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![BU of 8wng by Molmil](/molmil-images/mine/8wng) | Crystal structure of H. pylori isoleucyl-tRNA synthetase (HpIleRS) in complex with Ile | Descriptor: | ACETATE ION, GLYCEROL, ISOLEUCINE, ... | Authors: | Guo, Y, Li, S, Zhang, T. | Deposit date: | 2023-10-05 | Release date: | 2024-02-14 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structural basis for substrate and antibiotic recognition by Helicobacter pylori isoleucyl-tRNA synthetase. Febs Lett., 598, 2024
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8WNF
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![BU of 8wnf by Molmil](/molmil-images/mine/8wnf) | Crystal structure of H. pylori isoleucyl-tRNA synthetase (HpIleRS) in apo form | Descriptor: | ACETATE ION, GLYCEROL, Isoleucine--tRNA ligase, ... | Authors: | Guo, Y, Li, S, Zhang, T. | Deposit date: | 2023-10-05 | Release date: | 2024-02-14 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for substrate and antibiotic recognition by Helicobacter pylori isoleucyl-tRNA synthetase. Febs Lett., 598, 2024
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8WMY
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![BU of 8wmy by Molmil](/molmil-images/mine/8wmy) | Crystal structure of YqeK in complex with MG and ADP. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, bis(5'-nucleosyl)-tetraphosphatase (symmetrical) | Authors: | Mo, X. | Deposit date: | 2023-10-05 | Release date: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Molecular Mechanism of Ap4A Hydrolysis by YqeK of Staphylococcus pyogenes. To be published
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8WMT
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8WML
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8WMI
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8WMF
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![BU of 8wmf by Molmil](/molmil-images/mine/8wmf) | Structure of the SARS-CoV-2 EG.5.1 spike glycoprotein (closed-1 state) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Nomai, T, Anraku, Y, Kita, S, Hashiguchi, T, Maenaka, K. | Deposit date: | 2023-10-03 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.51 Å) | Cite: | Virological characteristics of the SARS-CoV-2 Omicron EG.5.1 variant Biorxiv, 2024
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8WMD
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![BU of 8wmd by Molmil](/molmil-images/mine/8wmd) | Structure of the SARS-CoV-2 EG.5.1 spike glycoprotein (closed-2 state) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Nomai, T, Anraku, Y, Kita, S, Hashiguchi, T, Maenaka, K. | Deposit date: | 2023-10-03 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.71 Å) | Cite: | Virological characteristics of the SARS-CoV-2 Omicron EG.5.1 variant Biorxiv, 2024
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8WMC
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8WM4
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![BU of 8wm4 by Molmil](/molmil-images/mine/8wm4) | Cryo-EM structure of DiCas7-11 in complex with crRNA | Descriptor: | CRISPR-associated RAMP family protein, ZINC ION, crRNA (38-MER) | Authors: | Ma, H.Y, Tang, X.D. | Deposit date: | 2023-10-02 | Release date: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | Structural basis of negative regulation of CRISPR-Cas7-11 by TPR-CHAT. Signal Transduct Target Ther, 9, 2024
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8WM0
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![BU of 8wm0 by Molmil](/molmil-images/mine/8wm0) | Crystal structure of TNIK-thiopeptide wTP3 complex | Descriptor: | ADENOSINE, THIOPEPTIDE wTP3, TRAF2 and NCK-interacting protein kinase | Authors: | Hamada, K, Kobayashi, S, Vinogradov, A.A, Zhang, Y, Goto, Y, Suga, H, Ogata, K, Sengoku, T. | Deposit date: | 2023-10-01 | Release date: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A Compact Reprogrammed Genetic Code for De Novo Discovery of Proteolytically Stable Thiopeptides. J.Am.Chem.Soc., 2024
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8WLS
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8WLG
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![BU of 8wlg by Molmil](/molmil-images/mine/8wlg) | Crystal structure of Cypovirus Polyhedra mutant fused with c-Myc fragment | Descriptor: | Polyhedrin,Myc proto-oncogene protein | Authors: | Kojima, M, Ueno, T, Abe, S, Hirata, K. | Deposit date: | 2023-09-29 | Release date: | 2024-06-05 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | High-throughput structure determination of an intrinsically disordered protein using cell-free protein crystallization. Proc.Natl.Acad.Sci.USA, 121, 2024
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8WKU
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8WKH
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![BU of 8wkh by Molmil](/molmil-images/mine/8wkh) | Crystal structure of group 13 allergen from Blomia tropicalis | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, Fatty acid-binding protein | Authors: | Zhu, K.L, Gong, Y, Cui, Y.B. | Deposit date: | 2023-09-27 | Release date: | 2023-11-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Immunobiological properties and structure analysis of group 13 allergen from Blomia tropicalis and its IgE-mediated cross-reactivity. Int.J.Biol.Macromol., 254, 2023
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8WJY
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![BU of 8wjy by Molmil](/molmil-images/mine/8wjy) | PKMYT1_Cocrystal_Cpd 4 | Descriptor: | DIMETHYL SULFOXIDE, GLYCEROL, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase, ... | Authors: | Wang, Y, Wang, C, Liu, T, Qi, H, Chen, S, Cai, X, Zhang, M, Aliper, A, Ren, F, Ding, X, Zhavoronkov, A. | Deposit date: | 2023-09-26 | Release date: | 2023-11-22 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Discovery of Tetrahydropyrazolopyrazine Derivatives as Potent and Selective MYT1 Inhibitors for the Treatment of Cancer. J.Med.Chem., 67, 2024
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8WIM
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![BU of 8wim by Molmil](/molmil-images/mine/8wim) | Crystal structure of Jingmen tick virus RNA-dependent RNA polymerase (D307 construct) | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Jingmen tick virus NSP1, ... | Authors: | Wang, X, Jing, X, Deng, F, Gong, P. | Deposit date: | 2023-09-24 | Release date: | 2024-01-17 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | A jingmenvirus RNA-dependent RNA polymerase structurally resembles the flavivirus counterpart but with different features at the initiation phase. Nucleic Acids Res., 52, 2024
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8WIL
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![BU of 8wil by Molmil](/molmil-images/mine/8wil) | Crystal structure of Jingmen tick virus RNA-dependent RNA polymerase (D55 construct) | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Jingmen tick virus NSP1, ... | Authors: | Wang, X, Jing, X, Deng, F, Gong, P. | Deposit date: | 2023-09-24 | Release date: | 2024-01-17 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A jingmenvirus RNA-dependent RNA polymerase structurally resembles the flavivirus counterpart but with different features at the initiation phase. Nucleic Acids Res., 52, 2024
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8WGW
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![BU of 8wgw by Molmil](/molmil-images/mine/8wgw) | Local refinement of RBD-ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | Wei, X, Zhang, Z. | Deposit date: | 2023-09-22 | Release date: | 2024-02-28 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis. Nat.Immunol., 25, 2024
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8WGV
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![BU of 8wgv by Molmil](/molmil-images/mine/8wgv) | BA.2(S375) Spike (S6P)/hACE2 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | Wei, X, Zhang, Z. | Deposit date: | 2023-09-22 | Release date: | 2024-02-28 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis. Nat.Immunol., 25, 2024
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8WGQ
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![BU of 8wgq by Molmil](/molmil-images/mine/8wgq) | The Crystal Structure of L-asparaginase from Biortus. | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, L-asparaginase | Authors: | Wang, F, Cheng, W, Lv, Z, Ju, C, Wang, J. | Deposit date: | 2023-09-22 | Release date: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | The Crystal Structure of L-asparaginase from Biortus. To Be Published
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8WG8
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![BU of 8wg8 by Molmil](/molmil-images/mine/8wg8) | Cryo-EM structures of peptide free and Gs-coupled GCGR | Descriptor: | Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Cong, Z.T, Zhao, F.H, Li, Y, Luo, G, Zhou, Q.T, Yang, D.H, Wang, M.W. | Deposit date: | 2023-09-20 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.71 Å) | Cite: | Molecular features of the ligand-free GLP-1R, GCGR and GIPR in complex with G s proteins. Cell Discov, 10, 2024
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