8WMC

Cryo-EM structure of DiCas7-11-crRNA in complex with regulator

Summary for 8WMC

• Entry DOI: 10.2210/pdb8wmc/pdb
• EMDB information: 37640 37649
• Descriptor: CHAT domain-containing protein, CRISPR-associated RAMP family protein, RNA (38-MER), ... (4 entities in total)
• Functional Keywords: crispr-cas, gene editing, tpr-chat, immune system
• Biological source: Desulfonema ishimotonii; More
• Total number of polymer chains: 3
• Total formula weight: 284640.64

Authors

Ma, H.Y.,Tang, X.D. (deposition date: 2023-10-03, release date: 2024-05-29)

• Primary citation: Hong, T.,Luo, Q.,Ma, H.,Wang, X.,Li, X.,Shen, C.,Pang, J.,Wang, Y.,Chen, Y.,Zhang, C.,Su, Z.,Dong, H.,Tang, X.; Structural basis of negative regulation of CRISPR-Cas7-11 by TPR-CHAT.; Signal Transduct Target Ther, 9:111-111, 2024; PubMed: 38735995; DOI: 10.1038/s41392-024-01821-4

Experimental method

ELECTRON MICROSCOPY (2.9 Å)