8WM0
Crystal structure of TNIK-thiopeptide wTP3 complex
Summary for 8WM0
| Entry DOI | 10.2210/pdb8wm0/pdb |
| Descriptor | TRAF2 and NCK-interacting protein kinase, THIOPEPTIDE wTP3, ADENOSINE, ... (4 entities in total) |
| Functional Keywords | ripp, thiopeptide, kinase inhibition, complex, signaling protein, signaling protein-inhibitor complex |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 37247.38 |
| Authors | Hamada, K.,Kobayashi, S.,Vinogradov, A.A.,Zhang, Y.,Goto, Y.,Suga, H.,Ogata, K.,Sengoku, T. (deposition date: 2023-10-01, release date: 2024-03-27) |
| Primary citation | Vinogradov, A.A.,Zhang, Y.,Hamada, K.,Kobayashi, S.,Ogata, K.,Sengoku, T.,Goto, Y.,Suga, H. A Compact Reprogrammed Genetic Code for De Novo Discovery of Proteolytically Stable Thiopeptides. J.Am.Chem.Soc., 2024 Cited by PubMed: 38491946DOI: 10.1021/jacs.3c12037 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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