8WGV
BA.2(S375) Spike (S6P)/hACE2 complex
Summary for 8WGV
Entry DOI | 10.2210/pdb8wgv/pdb |
EMDB information | 37516 |
Descriptor | Spike glycoprotein, Angiotensin-converting enzyme 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | complex, viral protein/hydrolase, viral protein-hydrolase complex |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) More |
Total number of polymer chains | 6 |
Total formula weight | 639705.00 |
Authors | |
Primary citation | He, X.,Zhang, X.,Wu, B.,Deng, J.,Zhang, Y.,Zhu, A.,Yuan, Y.,Lin, Y.,Chen, A.,Feng, J.,Wang, X.,Wu, S.,Liu, Y.,Liu, J.,Wang, Y.,Li, R.,Liang, C.,Yuan, Q.,Liang, Y.,Fang, Q.,Xi, Z.,Li, W.,Liang, L.,Zhang, Z.,Tang, H.,Peng, Y.,Ke, C.,Ma, X.,Cai, W.,Pan, T.,Liu, B.,Deng, K.,Chen, J.,Zhao, J.,Wei, X.,Chen, R.,Zhang, Y.,Zhang, H. The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis. Nat.Immunol., 25:622-632, 2024 Cited by PubMed: 38454157DOI: 10.1038/s41590-024-01776-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.92 Å) |
Structure validation
Download full validation report