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6UIA
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BU of 6uia by Molmil
Structure of ATP citrate lyase with CoA in a partially open conformation
Descriptor: ATP-citrate synthase, COENZYME A
Authors:Wei, X, Marmorstein, R.
Deposit date:2019-09-30
Release date:2019-12-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Molecular basis for acetyl-CoA production by ATP-citrate lyase.
Nat.Struct.Mol.Biol., 27, 2020
6POE
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BU of 6poe by Molmil
Structure of ACLY in complex with CoA
Descriptor: ATP-citrate synthase, COENZYME A
Authors:Wei, X, Marmorstein, R.
Deposit date:2019-07-03
Release date:2019-12-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Molecular basis for acetyl-CoA production by ATP-citrate lyase.
Nat.Struct.Mol.Biol., 27, 2020
7RIG
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BU of 7rig by Molmil
Structure of ACLY-D1026A-substrates
Descriptor: (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ...
Authors:Wei, X, Marmorstein, R.
Deposit date:2021-07-19
Release date:2023-05-10
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023
7RKZ
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BU of 7rkz by Molmil
Structure of ACLY D1026A-substrates-asym-int
Descriptor: (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ...
Authors:Wei, X, Marmorstein, R.
Deposit date:2021-07-22
Release date:2023-05-10
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023
7RMP
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BU of 7rmp by Molmil
Structure of ACLY D1026A - substrates-asym
Descriptor: (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ...
Authors:Wei, X, Marmorstein, R.
Deposit date:2021-07-28
Release date:2023-05-10
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023
6UI9
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BU of 6ui9 by Molmil
Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate
Descriptor: ACETYL COENZYME *A, ACLY, OXALOACETATE ION
Authors:Wei, X, Marmorstein, R.
Deposit date:2019-09-30
Release date:2019-12-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular basis for acetyl-CoA production by ATP-citrate lyase
Nat.Struct.Mol.Biol., 27, 2020
6UV5
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BU of 6uv5 by Molmil
Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate
Descriptor: ACETYL COENZYME *A, ATP citrate lyase, OXALOACETATE ION
Authors:Wei, X, Marmorstein, R.
Deposit date:2019-11-01
Release date:2019-12-25
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular basis for acetyl-CoA production by ATP-citrate lyase.
Nat.Struct.Mol.Biol., 27, 2020
6UUW
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BU of 6uuw by Molmil
Structure of human ATP citrate lyase E599Q mutant in complex with Mg2+, citrate, ATP and CoA
Descriptor: (2S)-2-hydroxy-2-[2-oxo-2-(phosphonooxy)ethyl]butanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ...
Authors:Wei, X, Marmorstein, R.
Deposit date:2019-11-01
Release date:2019-12-25
Last modified:2021-08-11
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Molecular basis for acetyl-CoA production by ATP-citrate lyase
Nat.Struct.Mol.Biol., 27, 2020
6POF
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BU of 6pof by Molmil
Structure of human ATP citrate lyase
Descriptor: ATP-citrate synthase
Authors:Wei, X, Marmorstein, R.
Deposit date:2019-07-03
Release date:2020-01-01
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Molecular basis for acetyl-CoA production by ATP-citrate lyase.
Nat.Struct.Mol.Biol., 27, 2020
7LJ9
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BU of 7lj9 by Molmil
Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate
Descriptor: ACETYL COENZYME *A, ATP-citrate synthase, OXALOACETATE ION
Authors:Wei, X, Marmorstein, R.
Deposit date:2021-01-28
Release date:2021-03-31
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase.
Nat.Struct.Mol.Biol., 28, 2021
7SNH
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BU of 7snh by Molmil
Structure of G6PD-D200N tetramer bound to NADP+
Descriptor: Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Wei, X, Marmorstein, R.
Deposit date:2021-10-28
Release date:2022-07-13
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Allosteric role of a structural NADP + molecule in glucose-6-phosphate dehydrogenase activity.
Proc.Natl.Acad.Sci.USA, 119, 2022
7SNF
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BU of 7snf by Molmil
Structure of G6PD-WT dimer
Descriptor: Glucose-6-phosphate 1-dehydrogenase
Authors:Wei, X, Marmorstein, R.
Deposit date:2021-10-28
Release date:2022-07-13
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Allosteric role of a structural NADP + molecule in glucose-6-phosphate dehydrogenase activity.
Proc.Natl.Acad.Sci.USA, 119, 2022
7SNI
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BU of 7sni by Molmil
Structure of G6PD-D200N tetramer bound to NADP+ and G6P
Descriptor: 6-O-phosphono-beta-D-glucopyranose, Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Wei, X, Marmorstein, R.
Deposit date:2021-10-28
Release date:2022-07-13
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Allosteric role of a structural NADP + molecule in glucose-6-phosphate dehydrogenase activity.
Proc.Natl.Acad.Sci.USA, 119, 2022
7SNG
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BU of 7sng by Molmil
structure of G6PD-WT tetramer
Descriptor: Glucose-6-phosphate 1-dehydrogenase
Authors:Wei, X, Marmorstein, R.
Deposit date:2021-10-28
Release date:2022-07-13
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Allosteric role of a structural NADP + molecule in glucose-6-phosphate dehydrogenase activity.
Proc.Natl.Acad.Sci.USA, 119, 2022
7TOF
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BU of 7tof by Molmil
Structure of G6PD-WT dimer with no symmetry applied
Descriptor: Glucose-6-phosphate 1-dehydrogenase
Authors:Wei, X, Marmorstein, R.
Deposit date:2022-01-24
Release date:2022-09-14
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Allosteric role of a structural NADP + molecule in glucose-6-phosphate dehydrogenase activity.
Proc.Natl.Acad.Sci.USA, 119, 2022
7TOE
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BU of 7toe by Molmil
Structure of G6PD-WT tetramer with no symmetry imposed
Descriptor: Glucose-6-phosphate 1-dehydrogenase
Authors:Wei, X, Marmorstein, R.
Deposit date:2022-01-24
Release date:2022-09-14
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Allosteric role of a structural NADP + molecule in glucose-6-phosphate dehydrogenase activity.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UAL
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BU of 7ual by Molmil
Structure of G6PD-D200N tetramer bound to NADP+ and G6P with no symmetry applied
Descriptor: 6-O-phosphono-beta-D-glucopyranose, Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Wei, X, Marmorstein, R.
Deposit date:2022-03-13
Release date:2022-09-14
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Allosteric role of a structural NADP + molecule in glucose-6-phosphate dehydrogenase activity.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UC2
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BU of 7uc2 by Molmil
Structure of G6PD-D200N tetramer bound to NADP+ with no symmetry applied
Descriptor: Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Wei, X, Marmorstein, R.
Deposit date:2022-03-15
Release date:2022-09-14
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Allosteric role of a structural NADP + molecule in glucose-6-phosphate dehydrogenase activity.
Proc.Natl.Acad.Sci.USA, 119, 2022
7LIW
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BU of 7liw by Molmil
Local refinement of human ATP citrate lyase E599Q mutant ASH domain
Descriptor: (2S)-2-hydroxy-2-[2-oxo-2-(phosphonooxy)ethyl]butanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ...
Authors:Wei, X, Marmorstein, R.
Deposit date:2021-01-28
Release date:2021-05-19
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase.
Nat.Struct.Mol.Biol., 28, 2021
7LLA
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BU of 7lla by Molmil
Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate (EM map was generated in Cryosparc with non-uniform refinement)
Descriptor: ACETYL COENZYME *A, ATP-citrate synthase, OXALOACETATE ION
Authors:Wei, X, Marmorstein, R.
Deposit date:2021-02-03
Release date:2021-03-03
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase.
Nat.Struct.Mol.Biol., 28, 2021
7UAG
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BU of 7uag by Molmil
Structure of G6PD-WT dimer
Descriptor: Glucose-6-phosphate 1-dehydrogenase
Authors:Wei, X, Marmorstein, R.
Deposit date:2022-03-12
Release date:2023-03-15
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of G6PD-WT dimer
To Be Published
7WL5
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BU of 7wl5 by Molmil
Structure of an avian influenza H5 hemagglutinin from the influenza virus A/Equine/Guangxi/25/2010(H5N1) and A/Equine/Guangxi/68/2010(H5N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Wei, X, Yang, X, Chen, Q, Meng, G.
Deposit date:2022-01-12
Release date:2023-01-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of an avian influenza H5 hemagglutinin from the influenza virus A/Equine/Guangxi/25/2010(H5N1) and A/Equine/Guangxi/68/2010(H5N1)
To Be Published
8G5D
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BU of 8g5d by Molmil
Structure of ACLY-D1026A-products, local refinement of ASH domain
Descriptor: (3S)-citryl-Coenzyme A, ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Wei, X, Marmorstein, R.
Deposit date:2023-02-13
Release date:2023-05-10
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023
8G1F
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BU of 8g1f by Molmil
Structure of ACLY-D1026A-products
Descriptor: (3S)-citryl-Coenzyme A, ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Wei, X, Marmorstein, R.
Deposit date:2023-02-02
Release date:2023-05-10
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023
8G1E
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BU of 8g1e by Molmil
Structure of ACLY-D1026A-products-asym
Descriptor: (3S)-citryl-Coenzyme A, ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Wei, X, Marmorstein, R.
Deposit date:2023-02-02
Release date:2023-05-10
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023

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