6UV5

Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate

Summary for 6UV5

Entry DOI	10.2210/pdb6uv5/pdb
EMDB information	20904
Descriptor	ATP citrate lyase, ACETYL COENZYME *A, OXALOACETATE ION, ... (4 entities in total)
Functional Keywords	lyase
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	487698.55
Authors	Wei, X.,Marmorstein, R. (deposition date: 2019-11-01, release date: 2019-12-25, Last modification date: 2024-03-06)
Primary citation	Wei, X.,Schultz, K.,Bazilevsky, G.A.,Vogt, A.,Marmorstein, R. Molecular basis for acetyl-CoA production by ATP-citrate lyase. Nat.Struct.Mol.Biol., 27:33-41, 2020 Cited by PubMed: 31873304 DOI: 10.1038/s41594-019-0351-6 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.4 Å)

Structure validation