7LLA
Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate (EM map was generated in Cryosparc with non-uniform refinement)
Summary for 7LLA
| Entry DOI | 10.2210/pdb7lla/pdb |
| EMDB information | 20783 23413 |
| Descriptor | ATP-citrate synthase, ACETYL COENZYME *A, OXALOACETATE ION (3 entities in total) |
| Functional Keywords | lyase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 4 |
| Total formula weight | 488223.36 |
| Authors | Wei, X.,Marmorstein, R. (deposition date: 2021-02-03, release date: 2021-03-03, Last modification date: 2024-05-29) |
| Primary citation | Wei, X.,Marmorstein, R. Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase. Nat.Struct.Mol.Biol., 28:639-641, 2021 Cited by PubMed: 34294921DOI: 10.1038/s41594-021-00625-2 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.97 Å) |
Structure validation
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