7LIW

Local refinement of human ATP citrate lyase E599Q mutant ASH domain

Summary for 7LIW

Entry DOI	10.2210/pdb7liw/pdb
Related	6uuw
EMDB information	23387
Descriptor	ATP-citrate synthase, ADENOSINE-5'-DIPHOSPHATE, COENZYME A, ... (4 entities in total)
Functional Keywords	lyase
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	485399.40
Authors	Wei, X.,Marmorstein, R. (deposition date: 2021-01-28, release date: 2021-05-19, Last modification date: 2021-08-25)
Primary citation	Wei, X.,Marmorstein, R. Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase. Nat.Struct.Mol.Biol., 28:639-641, 2021 Cited by PubMed: 34294921 DOI: 10.1038/s41594-021-00625-2 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.85 Å)

Structure validation