6UUW

Structure of human ATP citrate lyase E599Q mutant in complex with Mg2+, citrate, ATP and CoA

Summary for 6UUW

Entry DOI	10.2210/pdb6uuw/pdb
EMDB information	20902
Descriptor	ATP-citrate synthase, ADENOSINE-5'-DIPHOSPHATE, COENZYME A, ... (6 entities in total)
Functional Keywords	lyase
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	489799.92
Authors	Wei, X.,Marmorstein, R. (deposition date: 2019-11-01, release date: 2019-12-25, Last modification date: 2024-05-29)
Primary citation	Wei, X.,Schultz, K.,Bazilevsky, G.A.,Vogt, A.,Marmorstein, R. Molecular basis for acetyl-CoA production by ATP-citrate lyase Nat.Struct.Mol.Biol., 27:33-41, 2020 Cited by PubMed: 31873304 DOI: 10.1038/s41594-019-0351-6 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.85 Å)

Structure validation