7UC2

Structure of G6PD-D200N tetramer bound to NADP+ with no symmetry applied

Summary for 7UC2

• Entry DOI: 10.2210/pdb7uc2/pdb
• EMDB information: 26442
• Descriptor: Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
• Functional Keywords: glucose-6-phosphate 1-dehydrogenase, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 247558.29

Authors

Wei, X.,Marmorstein, R. (deposition date: 2022-03-15, release date: 2022-09-14)

• Primary citation: Wei, X.,Kixmoeller, K.,Baltrusaitis, E.,Yang, X.,Marmorstein, R.; Allosteric role of a structural NADP + molecule in glucose-6-phosphate dehydrogenase activity.; Proc.Natl.Acad.Sci.USA, 119:e2119695119-e2119695119, 2022; PubMed: 35858355; DOI: 10.1073/pnas.2119695119

Experimental method

ELECTRON MICROSCOPY (2.5 Å)