7UC2
Structure of G6PD-D200N tetramer bound to NADP+ with no symmetry applied
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glucose-6-phosphate 1-dehydrogenase | polymer | 523 | 60402.8 | 4 | UniProt (P11413) Pfam (PF00479) Pfam (PF02781) | Homo sapiens (human) | G6PD |
| 2 | E, F, G, H, I... (A, B, C, D) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 8 | Chemie (NAP) | |||
| 3 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 28 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 515 (UniProt: P11413)
| PDB | External Database | Details |
|---|---|---|
| Asn 200 | Asp 200 | engineered mutation |
| Leu 516 | - | expression tag |
| Glu 517 | - | expression tag |
| His 518 | - | expression tag |
| His 519 | - | expression tag |
| His 520 | - | expression tag |
| His 521 | - | expression tag |
| His 522 | - | expression tag |
| His 523 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 241611.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 5947.2 | |
| All* | Total formula weight | 247558.3 |
