8WGW

Local refinement of RBD-ACE2

Summary for 8WGW

• Entry DOI: 10.2210/pdb8wgw/pdb
• EMDB information: 37517
• Descriptor: Spike glycoprotein, Angiotensin-converting enzyme 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: complex, viral protein/hydrolase, viral protein-hydrolase complex
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); More
• Total number of polymer chains: 2
• Total formula weight: 210982.21

Authors

Wei, X.,Zhang, Z. (deposition date: 2023-09-22, release date: 2024-02-28, Last modification date: 2024-04-24)

• Primary citation: He, X.,Zhang, X.,Wu, B.,Deng, J.,Zhang, Y.,Zhu, A.,Yuan, Y.,Lin, Y.,Chen, A.,Feng, J.,Wang, X.,Wu, S.,Liu, Y.,Liu, J.,Wang, Y.,Li, R.,Liang, C.,Yuan, Q.,Liang, Y.,Fang, Q.,Xi, Z.,Li, W.,Liang, L.,Zhang, Z.,Tang, H.,Peng, Y.,Ke, C.,Ma, X.,Cai, W.,Pan, T.,Liu, B.,Deng, K.,Chen, J.,Zhao, J.,Wei, X.,Chen, R.,Zhang, Y.,Zhang, H.; The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis.; Nat.Immunol., 25:622-632, 2024; PubMed: 38454157; DOI: 10.1038/s41590-024-01776-2

Experimental method

ELECTRON MICROSCOPY (2.9 Å)