8WMI

Cryo-EM structure of DiCas7-11 mutant in complex with crRNA

Summary for 8WMI

• Entry DOI: 10.2210/pdb8wmi/pdb
• EMDB information: 37640 37649 37653
• Descriptor: crRNA (39-MER), CRISPR-associated RAMP family protein, ZINC ION (3 entities in total)
• Functional Keywords: crispr-cas, gene editing, immune system
• Biological source: Escherichia coli; More
• Total number of polymer chains: 2
• Total formula weight: 196569.96

Authors

Ma, H.Y.,Tang, X.D. (deposition date: 2023-10-03, release date: 2024-05-29)

• Primary citation: Hong, T.,Luo, Q.,Ma, H.,Wang, X.,Li, X.,Shen, C.,Pang, J.,Wang, Y.,Chen, Y.,Zhang, C.,Su, Z.,Dong, H.,Tang, X.; Structural basis of negative regulation of CRISPR-Cas7-11 by TPR-CHAT.; Signal Transduct Target Ther, 9:111-111, 2024; PubMed: 38735995; DOI: 10.1038/s41392-024-01821-4

Experimental method

ELECTRON MICROSCOPY (3.53 Å)