3JBP
| Cryo-electron microscopy reconstruction of the Plasmodium falciparum 80S ribosome bound to E-tRNA | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein eS1, ... | Authors: | Sun, M, Li, W, Blomqvist, K, Das, S, Hashem, Y, Dvorin, J.D, Frank, J. | Deposit date: | 2015-09-16 | Release date: | 2015-10-14 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (6.7 Å) | Cite: | Dynamical features of the Plasmodium falciparum ribosome during translation. Nucleic Acids Res., 43, 2015
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3JBN
| Cryo-electron microscopy reconstruction of the Plasmodium falciparum 80S ribosome bound to P-tRNA | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein eS1, ... | Authors: | Sun, M, Li, W, Blomqvist, K, Das, S, Hashem, Y, Dvorin, J.D, Frank, J. | Deposit date: | 2015-09-16 | Release date: | 2015-10-14 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Dynamical features of the Plasmodium falciparum ribosome during translation. Nucleic Acids Res., 43, 2015
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4M5D
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8D6J
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3J80
| CryoEM structure of 40S-eIF1-eIF1A preinitiation complex | Descriptor: | 18S rRNA, MAGNESIUM ION, RACK1, ... | Authors: | Hussain, T, Llacer, J.L, Fernandez, I.S, Savva, C.G, Ramakrishnan, V. | Deposit date: | 2014-08-28 | Release date: | 2014-11-05 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Structural changes enable start codon recognition by the eukaryotic translation initiation complex. Cell(Cambridge,Mass.), 159, 2014
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2FK6
| Crystal Structure of RNAse Z/tRNA(Thr) complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, RIBONUCLEASE Z, ... | Authors: | Li de la Sierra-Gallay, I, Mathy, N, Pellegrini, O, Condon, C. | Deposit date: | 2006-01-04 | Release date: | 2006-03-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of the ubiquitous 3' processing enzyme RNase Z bound to transfer RNA. Nat.Struct.Mol.Biol., 13, 2006
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4TYY
| DEAD-box helicase Mss116 bound to ssRNA and CDP-BeF | Descriptor: | ATP-dependent RNA helicase MSS116, mitochondrial, BERYLLIUM TRIFLUORIDE ION, ... | Authors: | Mallam, A.L, Sidote, D.J, Lambowitz, A.M. | Deposit date: | 2014-07-09 | Release date: | 2014-12-31 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase. Elife, 3, 2014
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4TYW
| DEAD-box helicase Mss116 bound to ssRNA and ADP-BeF | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase MSS116, mitochondrial, ... | Authors: | Mallam, A.L, Sidote, D.J, Lambowitz, A.M. | Deposit date: | 2014-07-09 | Release date: | 2014-12-31 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.197 Å) | Cite: | Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase. Elife, 3, 2014
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4TZ6
| DEAD-box helicase Mss116 bound to ssRNA and UDP-BeF | Descriptor: | ATP-dependent RNA helicase MSS116, mitochondrial, BERYLLIUM TRIFLUORIDE ION, ... | Authors: | Mallam, A.L, Sidote, D.J, Lambowitz, A.M. | Deposit date: | 2014-07-09 | Release date: | 2015-01-28 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.209 Å) | Cite: | Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase. Elife, 3, 2014
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3J7P
| Structure of the 80S mammalian ribosome bound to eEF2 | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | Authors: | Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S. | Deposit date: | 2014-08-01 | Release date: | 2014-09-03 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution. Cell(Cambridge,Mass.), 157, 2014
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7OF1
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5WNV
| Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | Descriptor: | (1R,2S,3S,4R,6R)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-alpha-L-altropyranosyl)-beta-L-arabinofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-allopyranoside, 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, ... | Authors: | DeMirci, H. | Deposit date: | 2017-08-01 | Release date: | 2018-02-21 | Last modified: | 2020-10-21 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | 2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation. Nat. Struct. Mol. Biol., 25, 2018
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6OGZ
| In situ structure of Rotavirus RNA-dependent RNA polymerase at transcript-elongated state | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Inner capsid protein VP2, RNA (5'-R(P*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*A)-3'), ... | Authors: | Ding, K, Chang, T, Shen, W, Roy, P, Zhou, Z.H. | Deposit date: | 2019-04-03 | Release date: | 2019-05-22 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | In situ structures of rotavirus polymerase in action and mechanism of mRNA transcription and release. Nat Commun, 10, 2019
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7ABI
| Human pre-Bact-2 spliceosome | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Beta-catenin-like protein 1, ... | Authors: | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | Deposit date: | 2020-09-07 | Release date: | 2021-02-10 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
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3LWP
| Structure of H/ACA RNP bound to a substrate RNA containing 5BrdU | Descriptor: | 5'-R(*GP*AP*GP*CP*GP*(BRU)P*GP*CP*GP*GP*UP*UP*U)-3, 50S ribosomal protein L7Ae, H/ACA RNA, ... | Authors: | Zhou, J, Liang, B, Lv, C, Yang, W, Li, H. | Deposit date: | 2010-02-24 | Release date: | 2010-07-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Glycosidic bond conformation preference plays a pivotal role in catalysis of RNA pseudouridylation: a combined simulation and structural study. J.Mol.Biol., 401, 2010
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3LWO
| Structure of H/ACA RNP bound to a substrate RNA containing 5BrU | Descriptor: | 5'-R(*GP*AP*GP*CP*GP*(5BU)P*GP*CP*GP*GP*UP*UP*U)-3', 50S ribosomal protein L7Ae, H/ACA RNA, ... | Authors: | Zhou, J, Liang, B, Lv, C, Yang, W, Li, H. | Deposit date: | 2010-02-24 | Release date: | 2010-07-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.855 Å) | Cite: | Glycosidic bond conformation preference plays a pivotal role in catalysis of RNA pseudouridylation: a combined simulation and structural study. J.Mol.Biol., 401, 2010
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7AHO
| RUVBL1-RUVBL2 heterohexameric ring after binding of RNA helicase DHX34 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2 | Authors: | Lopez-Perrote, A, Rodriguez, C.F, Llorca, O. | Deposit date: | 2020-09-25 | Release date: | 2020-11-25 | Method: | ELECTRON MICROSCOPY (4.18 Å) | Cite: | Regulation of RUVBL1-RUVBL2 AAA-ATPases by the nonsense-mediated mRNA decay factor DHX34, as evidenced by Cryo-EM. Elife, 9, 2020
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6HPJ
| Structure of human SRSF1 RRM1 bound to AACAAA RNA | Descriptor: | Immunoglobulin G-binding protein G,Serine/arginine-rich splicing factor 1, RNA (5'-R(*AP*AP*CP*AP*AP*A)-3') | Authors: | Allain, F.T.H, Clery, A. | Deposit date: | 2018-09-21 | Release date: | 2020-11-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of SRSF1 RRM1 bound to RNA reveals an unexpected bimodal mode of interaction and explains its involvement in SMN1 exon7 splicing. Nat Commun, 12, 2021
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5DE5
| Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA. | Descriptor: | Fragile X mental retardation protein 1, POTASSIUM ION, sc1 | Authors: | Vasilyev, N, Polonskaia, A, Darnell, J.C, Darnell, R.B, Patel, D.J, Serganov, A. | Deposit date: | 2015-08-25 | Release date: | 2015-09-23 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.0011 Å) | Cite: | Crystal structure reveals specific recognition of a G-quadruplex RNA by a beta-turn in the RGG motif of FMRP. Proc.Natl.Acad.Sci.USA, 112, 2015
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4WSB
| Bat Influenza A polymerase with bound vRNA promoter | Descriptor: | Influenza A polymerase vRNA promoter 3' end, Influenza A polymerase vRNA promoter 5' end, PHOSPHATE ION, ... | Authors: | Cusack, S, Pflug, A, Guilligay, D, Reich, S. | Deposit date: | 2014-10-26 | Release date: | 2014-11-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural insight into cap-snatching and RNA synthesis by influenza polymerase. Nature, 516, 2014
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4WSA
| Crystal structure of Influenza B polymerase bound to the vRNA promoter (FluB1 form) | Descriptor: | Influenza B vRNA promoter 3' end, Influenza B vRNA promoter 5' end, PA, ... | Authors: | Reich, S, Guilligay, D, Pflug, A, Cusack, S. | Deposit date: | 2014-10-26 | Release date: | 2014-11-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural insight into cap-snatching and RNA synthesis by influenza polymerase. Nature, 516, 2014
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4WRT
| Crystal structure of Influenza B polymerase with bound vRNA promoter (form FluB2) | Descriptor: | Influenza virus polymerase vRNA promoter 3' end, Influenza virus polymerase vRNA promoter 5' end, PA, ... | Authors: | Reich, S, Guilligay, D, Pflug, A, Cusack, S. | Deposit date: | 2014-10-25 | Release date: | 2014-11-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural insight into cap-snatching and RNA synthesis by influenza polymerase. Nature, 516, 2014
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6GQE
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5FMZ
| Crystal structure of Influenza B polymerase with bound 5' vRNA | Descriptor: | 5'-R(*AP*GP*UP*AP*GP*UP*AP*AP*CP*AP*AP*GP)-3', POLYMERASE ACIDIC PROTEIN, POLYMERASE BASIC PROTEIN 2, ... | Authors: | Guilligay, D, Cusack, S. | Deposit date: | 2015-11-10 | Release date: | 2016-01-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of Pb2 Domains. Mol.Cell, 61, 2016
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1OLN
| Model for thiostrepton antibiotic binding to L11 substrate from 50S ribosomal RNA | Descriptor: | 50S RIBOSOMAL PROTEIN L11, RNA, THIOSTREPTON | Authors: | Lentzen, G, Klinck, R, Matassova, N, Aboul-Ela, F, Murchie, A.I.H. | Deposit date: | 2003-08-08 | Release date: | 2003-09-11 | Last modified: | 2019-08-21 | Method: | SOLUTION NMR, THEORETICAL MODEL | Cite: | Structural Basis for Contrasting Activities of Ribosome Binding Thiazole Antibiotics Chem.Biol., 10, 2003
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