5DE5
Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA.
Summary for 5DE5
| Entry DOI | 10.2210/pdb5de5/pdb |
| Descriptor | sc1, Fragile X mental retardation protein 1, POTASSIUM ION, ... (4 entities in total) |
| Functional Keywords | fragile x syndrome, rna structure, rgg box, fmrp, g-quadruplex, rna binding protein-rna complex, rna binding protein/rna |
| Biological source | synthetic construct More |
| Total number of polymer chains | 4 |
| Total formula weight | 26771.21 |
| Authors | Vasilyev, N.,Polonskaia, A.,Darnell, J.C.,Darnell, R.B.,Patel, D.J.,Serganov, A. (deposition date: 2015-08-25, release date: 2015-09-23, Last modification date: 2024-03-06) |
| Primary citation | Vasilyev, N.,Polonskaia, A.,Darnell, J.C.,Darnell, R.B.,Patel, D.J.,Serganov, A. Crystal structure reveals specific recognition of a G-quadruplex RNA by a beta-turn in the RGG motif of FMRP. Proc.Natl.Acad.Sci.USA, 112:E5391-E5400, 2015 Cited by PubMed: 26374839DOI: 10.1073/pnas.1515737112 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.0011 Å) |
Structure validation
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