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7RQP
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Structure of PfCSP NPNV binding antibody L9
Descriptor: L9 Heavy Chain, L9 Kappa Chain
Authors:Hurlburt, N.K, Pancera, M.
Deposit date:2021-08-06
Release date:2022-03-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria.
Cell Rep, 38, 2022
7RQR
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Structure of chimeric antibody L9heavy_F10light with PfCSP peptide NANPNVDP
Descriptor: 1,2-ETHANEDIOL, F10 Kappa Chain, L9 Heavy Chain, ...
Authors:Hurlburt, N.K, Pancera, M.
Deposit date:2021-08-06
Release date:2022-03-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria.
Cell Rep, 38, 2022
7RQQ
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BU of 7rqq by Molmil
Structure of chimeric antibody F10heavy_L9light with PfCSP peptide NANPNVDP
Descriptor: 1,2-ETHANEDIOL, F10 Heavy Chain, L9 Kappa Chain, ...
Authors:Hurlburt, N.K, Pancera, M.
Deposit date:2021-08-06
Release date:2022-03-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria.
Cell Rep, 38, 2022
7RRG
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BU of 7rrg by Molmil
Crystal structure of human 0606T1-2 TCR bound to HLA-A*03:01 in complex with a mutant PIK3CA peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Ma, J, Baker, B.M.
Deposit date:2021-08-09
Release date:2022-03-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA.
Nat Med, 28, 2022
8A05
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BU of 8a05 by Molmil
Bacteriophage phiCjT23 spike protein penton domain
Descriptor: Spike protein P13 N-terminal, capsid internal domain, Unknown vertex protein
Authors:Rissanen, I, Huiskonen, J.T.
Deposit date:2022-05-26
Release date:2022-12-14
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structure of ssDNA bacteriophage Phi CjT23 provides insight into early virus evolution.
Nat Commun, 13, 2022
5OPI
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BU of 5opi by Molmil
Crystal structure of the TAPBPR-MHC I peptide editing complex
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ...
Authors:Thomas, C, Tampe, R.
Deposit date:2017-08-09
Release date:2017-10-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of the TAPBPR-MHC I complex defines the mechanism of peptide loading and editing.
Science, 358, 2017
7E8M
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BU of 7e8m by Molmil
Crystal structure of SARS-CoV-2 antibody P2C-1F11 with mutated RBD
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P2C-1F11 heavy chain, ...
Authors:Wang, X.Q, Zhang, L.Q, Ge, J.W, Wang, R.K, Lan, J.
Deposit date:2021-03-02
Release date:2021-05-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species.
Immunity, 54, 2021
7E6P
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BU of 7e6p by Molmil
Fab-amyloid beta fragment complex
Descriptor: 1,2-ETHANEDIOL, Amyloid beta fragment with an intramolecular disulfide bond at positions 17 and 28, DI(HYDROXYETHYL)ETHER, ...
Authors:Kita, A, Irie, K, Irie, Y, Miki, K.
Deposit date:2021-02-23
Release date:2022-01-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Characterization of a Conformation-Restricted Amyloid beta Peptide and Immunoreactivity of Its Antibody in Human AD brain.
Acs Chem Neurosci, 12, 2021
7L1C
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BU of 7l1c by Molmil
Crystal structure of HLA-A*03:01 in complex with a mutant PIK3CA peptide
Descriptor: Beta-2-microglobulin, FORMIC ACID, GLYCEROL, ...
Authors:Ma, J, Baker, B.M.
Deposit date:2020-12-14
Release date:2022-03-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA.
Nat Med, 28, 2022
7L1B
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Crystal structure of HLA-A*03:01 in complex with a wild-type PIK3CA peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Ma, J, Baker, B.M.
Deposit date:2020-12-14
Release date:2022-03-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA.
Nat Med, 28, 2022
7L1D
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BU of 7l1d by Molmil
Crystal structure of human 21LT2-2 TCR bound to HLA-A*03:01 in complex with a mutant PIK3CA peptide
Descriptor: ACETATE ION, Beta-2-microglobulin, GLYCEROL, ...
Authors:Ma, J, Baker, B.M.
Deposit date:2020-12-14
Release date:2022-03-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA.
Nat Med, 28, 2022
6BGA
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BU of 6bga by Molmil
2B4 I-Ek TCR-MHC complex with affinity-enhancing Velcro peptide
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B4 peptide,MHC I-Ek B chain, ...
Authors:Gee, M.H, Sibener, L.V, Birnbaum, M.E, Jude, K.M, Garcia, K.C.
Deposit date:2017-10-27
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.307 Å)
Cite:Stress-testing the relationship between T cell receptor/peptide-MHC affinity and cross-reactivity using peptide velcro.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5NQW
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BU of 5nqw by Molmil
IgE-Fc in complex with single domain antibody 026
Descriptor: 026, GLYCEROL, Immunoglobulin heavy constant epsilon, ...
Authors:Laursen, N.S, Jabs, F, Spillner, E, Andersen, G.R.
Deposit date:2017-04-21
Release date:2018-01-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts Fc epsilon RI interaction.
Nat Commun, 9, 2018
3PL6
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BU of 3pl6 by Molmil
Structure of Autoimmune TCR Hy.1B11 in complex with HLA-DQ1 and MBP 85-99
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MBP peptide / T-cell receptor beta chain chimera, MHC class II HLA-DQ-alpha chain, ...
Authors:Sethi, D.K, Wucherpfennig, K.W.
Deposit date:2010-11-13
Release date:2010-12-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC.
J.Exp.Med., 208, 2011
2OJT
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BU of 2ojt by Molmil
Structure and mechanism of kainate receptor modulation by anions
Descriptor: (S)-1-(2-AMINO-2-CARBOXYETHYL)-3(2-CARBOXYTHIOPHENE-3-YL-METHYL)-5-METHYLPYRIMIDINE-2,4-DIONE, BROMIDE ION, Glutamate receptor, ...
Authors:Mayer, M.L.
Deposit date:2007-01-14
Release date:2007-04-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure and mechanism of kainate receptor modulation by anions.
Neuron, 53, 2007
1OGA
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BU of 1oga by Molmil
A structural basis for immunodominant human T-cell receptor recognition.
Descriptor: BETA-2-MICROGLOBULIN, GILGFVFTL, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
Authors:Stewart-Jones, G.B.E, McMichael, A.J, Bell, J.I, Stuart, D.I, Jones, E.Y.
Deposit date:2003-04-28
Release date:2003-06-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A Structural Basis for Immunodominant Human T Cell Receptor Recognition
Nat.Immunol., 4, 2003
4ZP0
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BU of 4zp0 by Molmil
Crystal structure of E. coli multidrug transporter MdfA in complex with deoxycholate
Descriptor: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, LAURYL DIMETHYLAMINE-N-OXIDE, Multidrug transporter MdfA
Authors:Zhang, X.C, Heng, J, Zhao, Y, Wang, X.
Deposit date:2015-05-07
Release date:2015-08-19
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Substrate-bound structure of the E. coli multidrug resistance transporter MdfA
Cell Res., 25, 2015
4ZOW
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BU of 4zow by Molmil
Crystal structure of E. coli multidrug transporter MdfA in complex with chloramphenicol
Descriptor: CHLORAMPHENICOL, Multidrug transporter MdfA
Authors:Zhang, X.C, Heng, J, Zhao, Y, Wang, X.
Deposit date:2015-05-07
Release date:2015-08-19
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Substrate-bound structure of the E. coli multidrug resistance transporter MdfA
Cell Res., 25, 2015
4ZP2
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BU of 4zp2 by Molmil
Crystal structure of E. coli multidrug transporter MdfA in complex with n-dodecyl-N,N-dimethylamine-N-oxide
Descriptor: LAURYL DIMETHYLAMINE-N-OXIDE, Multidrug transporter MdfA
Authors:Zhang, X.C, Heng, J, Zhao, Y, Wang, X.
Deposit date:2015-05-07
Release date:2015-08-19
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Substrate-bound structure of the E. coli multidrug resistance transporter MdfA
Cell Res., 25, 2015
2QEJ
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BU of 2qej by Molmil
Crystal structure of a Staphylococcus aureus protein (SSL7) in complex with Fc of human IgA1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ...
Authors:Ramsland, P.A, Willoughby, N, Trist, H.M, Farrugia, W, Hogarth, P.M, Fraser, J.D, Wines, B.D.
Deposit date:2007-06-26
Release date:2007-09-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for evasion of IgA immunity by Staphylococcus aureus revealed in the complex of SSL7 with Fc of human IgA1
Proc.Natl.Acad.Sci.Usa, 104, 2007
3ECB
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BU of 3ecb by Molmil
Crystal structure of mouse H-2Dd in complex with peptide P18-I10 derived from human immunodeficiency virus envelope glycoprotein 120
Descriptor: 1,2-ETHANEDIOL, Beta-2 microglobulin, H-2 class I histocompatibility antigen, ...
Authors:Natarajan, K, Wang, R, Margulies, D.H.
Deposit date:2008-08-29
Release date:2009-07-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Structural basis of the CD8alphabeta/MHC class i interaction: focused recognition orients CD8beta to a T cell proximal position
J.Immunol., 183, 2009
2V17
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BU of 2v17 by Molmil
Structure of the complex of antibody MN423 with a fragment of tau protein
Descriptor: MONOCLONAL ANTIBODY FAB FRAGMENT MN423, PEPTIDE FRAGMENT
Authors:Sevcik, J, Skrabana, R, Csokova, N, Dvorsky, R, Novak, M.
Deposit date:2007-05-22
Release date:2007-12-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:X-Ray Structure of the Phf Core C-Terminus: Insight Into the Folding of the Intrinsically Disordered Protein Tau in Alzheimer'S Disease.
FEBS Lett., 581, 2007
5GJT
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BU of 5gjt by Molmil
Crystal structure of H1 hemagglutinin from A/Washington/05/2011 in complex with a neutralizing antibody 3E1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, heavy chain of human neutralizing antibody 3E1, ...
Authors:Wang, W, Zhang, T, Ding, J.
Deposit date:2016-07-01
Release date:2016-12-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses
Nat Commun, 7, 2016
5GJS
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BU of 5gjs by Molmil
Crystal structure of H1 hemagglutinin from A/California/04/2009 in complex with a neutralizing antibody 3E1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Wang, W, Zhang, T, Ding, J.
Deposit date:2016-07-01
Release date:2016-12-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses
Nat Commun, 7, 2016
5ITB
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BU of 5itb by Molmil
Crystal structure of the anti-RSV F Fab 14N4
Descriptor: anti-RSV F Fab 14N4 Heavy chain, anti-RSV F Fab 14N4 Light chain
Authors:Mousa, J.J, Crowe, J.E.
Deposit date:2016-03-16
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein.
Proc.Natl.Acad.Sci.USA, 113, 2016

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数据于2024-06-05公开中

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