3PL6

Structure of Autoimmune TCR Hy.1B11 in complex with HLA-DQ1 and MBP 85-99

Summary for 3PL6

Entry DOI	10.2210/pdb3pl6/pdb
Related	1YMM
Descriptor	MHC class II HLA-DQ-alpha chain, MHC class II HLA-DQ-beta chain, T-cell receptor alpha chain, ... (6 entities in total)
Functional Keywords	tcr-mhc complex, immunoglobulin fold, immune receptor, membrane, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	98356.15
Authors	Sethi, D.K.,Wucherpfennig, K.W. (deposition date: 2010-11-13, release date: 2010-12-22, Last modification date: 2024-03-13)
Primary citation	Sethi, D.K.,Schubert, D.A.,Anders, A.K.,Heroux, A.,Bonsor, D.A.,Thomas, C.P.,Sundberg, E.J.,Pyrdol, J.,Wucherpfennig, K.W. A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC. J.Exp.Med., 208:91-102, 2011 Cited by PubMed: 21199956 DOI: 10.1084/jem.20100725 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.55 Å)

Structure validation