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8GW6
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BU of 8gw6 by Molmil
AtSLAC1 6D mutant in closed state
Descriptor: CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, Guard cell S-type anion channel SLAC1,Green fluorescent protein (Fragment)
Authors:Lee, Y, Lee, S.
Deposit date:2022-09-16
Release date:2023-11-15
Last modified:2023-11-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model.
Nat Commun, 14, 2023
8GJP
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BU of 8gjp by Molmil
A1 Int graft: Adenylation domain 1 core construct from teicoplanin biosynthesis, intermediate selection pocket graft
Descriptor: MbtH-like short polypeptide, Non-ribosomal peptide synthetase
Authors:Hansen, M.H, Cryle, M.J.
Deposit date:2023-03-16
Release date:2023-12-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides.
Nat Commun, 14, 2023
8GLC
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BU of 8glc by Molmil
A1 AncAla: Adenylation domain 1 core construct from ancestral reconstruction of glycopeptide antibiotic biosynthesis, alanine selection pocket
Descriptor: MbtH-like short polypeptide, Non-ribosomal peptide synthetase
Authors:Hansen, M.H, Cryle, M.J.
Deposit date:2023-03-21
Release date:2023-12-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides.
Nat Commun, 14, 2023
6OPT
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BU of 6opt by Molmil
HIV-1 Protease NL4-3 V82F, I84V Mutant in complex with darunavir
Descriptor: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, Protease NL4-3, SULFATE ION
Authors:Lockbaum, G.J, Henes, M, Kosovrasti, K, Leidner, F, Nachum, G.S, Nalivaika, E.A, Bolon, D.N.A, KurtYilmaz, N, Schiffer, C.A.
Deposit date:2019-04-25
Release date:2019-09-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance.
Acs Chem.Biol., 14, 2019
6OPX
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BU of 6opx by Molmil
HIV-1 Protease NL4-3 I13V, G16E, V32I, L33F, K45I, M46I, L76V, V82F, I84V Mutant in complex with darunavir
Descriptor: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, Protease NL4-3
Authors:Lockbaum, G.J, Henes, M, Kosovrasti, K, Leidner, F, Nachum, G.S, Nalivaika, E.A, Bolon, D.N.A, KurtYilmaz, N, Schiffer, C.A.
Deposit date:2019-04-25
Release date:2019-09-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance.
Acs Chem.Biol., 14, 2019
8FPF
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BU of 8fpf by Molmil
Heterodimeric ABC transporter BmrCD in the inward-facing conformation bound to ATP: BmrCD_IF-ATP
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH, ...
Authors:Qingyu, T, Hassane, M.
Deposit date:2023-01-04
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter
Nat Commun, 14, 2023
4ODQ
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BU of 4odq by Molmil
Structure of SlyD delta-IF from Thermus thermophilus in complex with S3 peptide
Descriptor: 30S ribosomal protein S3, CALCIUM ION, CHLORIDE ION, ...
Authors:Quistgaard, E.M, Low, C, Nordlund, P.
Deposit date:2014-01-10
Release date:2015-01-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular insights into substrate recognition and catalytic mechanism of the chaperone and FKBP peptidyl-prolyl isomerase SlyD.
BMC Biol., 14, 2016
8FYG
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BU of 8fyg by Molmil
Crystal structure of Hyaluronate lyase A from Cutibacterium acnes
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Hyaluronate lyase
Authors:Katiki, M, McNally, R, Chatterjee, A, Hajam, I.A, Liu, G.Y, Murali, R.
Deposit date:2023-01-26
Release date:2023-12-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Functional divergence of a bacterial enzyme promotes healthy or acneic skin.
Nat Commun, 14, 2023
8FNX
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BU of 8fnx by Molmil
Crystal structure of Hyaluronate lyase B from Cutibacterium acnes
Descriptor: GLYCEROL, Hyaluronate lyase, PHOSPHATE ION
Authors:Katiki, M, McNally, R, Chatterjee, A, Hajam, I.A, Liu, G.Y, Murali, R.
Deposit date:2022-12-28
Release date:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Functional divergence of a bacterial enzyme promotes healthy or acneic skin.
Nat Commun, 14, 2023
8G0O
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BU of 8g0o by Molmil
Crystal structure of Y281F mutant of Hyaluronate lyase B from Cutibacterium acnes
Descriptor: Hyaluronate lyase
Authors:Katiki, M, McNally, R, Chatterjee, A, Hajam, I.A, Liu, G.Y, Murali, R.
Deposit date:2023-02-01
Release date:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Functional divergence of a bacterial enzyme promotes healthy or acneic skin.
Nat Commun, 14, 2023
6ONM
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BU of 6onm by Molmil
Crystal Structure of (+)-Limonene Synthase Complexed with 8,9-Difluorolinalyl Diphosphate
Descriptor: (+)-limonene synthase, (3R)-8-fluoro-7-(fluoromethyl)-3-methylocta-1,6-dien-3-yl trihydrogen diphosphate, MANGANESE (II) ION
Authors:Prem Kumar, R, Morehouse, B.R, Yu, Q, Oprian, D.D.
Deposit date:2019-04-22
Release date:2019-09-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Direct Evidence of an Enzyme-Generated LPP Intermediate in (+)-Limonene Synthase Using a Fluorinated GPP Substrate Analog.
Acs Chem.Biol., 14, 2019
8FP0
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BU of 8fp0 by Molmil
Ternary complex of CDK2 with small molecule ligands TW8672 and Roscovitine
Descriptor: 1,2-ETHANEDIOL, 2-{[2-(1H-indol-3-yl)ethyl]amino}-5-nitrobenzoic acid, Cyclin-dependent kinase 2, ...
Authors:Schonbrunn, E, Sun, L.
Deposit date:2023-01-03
Release date:2023-05-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding.
Nat Commun, 14, 2023
6OOI
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BU of 6ooi by Molmil
Crystal structure of triosephosphate isomerase from Schistosoma mansoni in complex with 2PG
Descriptor: 2-PHOSPHOGLYCOLIC ACID, CHLORIDE ION, GLYCEROL, ...
Authors:Jimenez-Sandoval, P, Brieba, L.
Deposit date:2019-04-23
Release date:2020-01-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Crystal structures of Triosephosphate Isomerases from Taenia solium and Schistosoma mansoni provide insights for vaccine rationale and drug design against helminth parasites.
Plos Negl Trop Dis, 14, 2020
8FAK
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BU of 8fak by Molmil
DNA replication fork binding triggers structural changes in the PriA DNA helicase that regulate the PriA-PriB replication restart pathway in E. coli
Descriptor: DNA (5'-D(P*CP*AP*GP*AP*CP*TP*CP*AP*TP*TP*TP*AP*GP*CP*CP*CP*TP*TP*AP*TP*CP*CP*G)-3'), DNA (5'-D(P*CP*GP*GP*AP*TP*AP*AP*GP*GP*GP*CP*TP*GP*AP*GP*CP*AP*CP*GP*CP*CP*GP*A)-3'), DNA (5'-D(P*TP*CP*GP*GP*CP*GP*TP*GP*CP*TP*C)-3'), ...
Authors:Duckworth, A.T, Ducos, P.L, McMillan, S.D, Satyshur, K.A, Blumenthal, K.H, Deorio, H.R, Larson, J.A, Sandler, S.J, Grant, T, Keck, J.L.
Deposit date:2022-11-28
Release date:2023-05-10
Last modified:2023-05-24
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Replication fork binding triggers structural changes in the PriA helicase that govern DNA replication restart in E. coli.
Nat Commun, 14, 2023
8G0Z
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BU of 8g0z by Molmil
Mutant bacteriophage T4 gp41 helicase hexamer bound with single strand DNA and ATPgammaS in the stalled primosome
Descriptor: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DnaB-like replicative helicase, MAGNESIUM ION, ...
Authors:Feng, X, Li, H.
Deposit date:2023-02-01
Release date:2023-06-14
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (3.61 Å)
Cite:Structural basis of the T4 bacteriophage primosome assembly and primer synthesis.
Nat Commun, 14, 2023
8FZY
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BU of 8fzy by Molmil
Bacteroides spp. Ntox15 domain type VI secretion system effector Tde1
Descriptor: 1,2-ETHANEDIOL, Ntox15 domain-containing protein, SULFATE ION
Authors:Bosch, D.E, Mougous, J.D.
Deposit date:2023-01-30
Release date:2023-07-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural disruption of Ntox15 nuclease effector domains by immunity proteins protects against type VI secretion system intoxication in Bacteroidales.
Mbio, 14, 2023
4YZW
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BU of 4yzw by Molmil
Crystal structure of AgPPO8
Descriptor: AGAP004976-PA, COPPER (II) ION
Authors:Hu, Y.
Deposit date:2015-03-25
Release date:2015-12-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The structure of a prophenoloxidase (PPO) from Anopheles gambiae provides new insights into the mechanism of PPO activation.
Bmc Biol., 14, 2016
8GIC
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BU of 8gic by Molmil
A1 Tei + Hpg: Adenylation domain 1 core construct from teicoplanin biosynthesis; 4-hydroxyphenylglycine bound
Descriptor: (2S)-AMINO(4-HYDROXYPHENYL)ACETIC ACID, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MbtH-like short polypeptide, ...
Authors:Hansen, M.H, Cryle, M.J.
Deposit date:2023-03-14
Release date:2023-12-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides.
Nat Commun, 14, 2023
6OPS
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BU of 6ops by Molmil
HIV-1 Protease NL4-3 WT in complex with darunavir
Descriptor: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, Protease NL4-3
Authors:Lockbaum, G.J, Henes, M, Kosovrasti, K, Leidner, F, Nachum, G.S, Nalivaika, E.A, Bolon, D.N.A, KurtYilmaz, N, Schiffer, C.A.
Deposit date:2019-04-25
Release date:2019-09-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance.
Acs Chem.Biol., 14, 2019
6OPW
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BU of 6opw by Molmil
HIV-1 Protease NL4-3 I13V, G16E, V32I, L33F, K45I, M46I, A71V, V82F, I84V Mutant in complex with darunavir
Descriptor: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, Protease NL4-3, SULFATE ION
Authors:Lockbaum, G.J, Henes, M, Kosovrasti, K, Leidner, F, Nachum, G.S, Nalivaika, E.A, Bolon, D.N.A, KurtYilmaz, N, Schiffer, C.A.
Deposit date:2019-04-25
Release date:2019-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance.
Acs Chem.Biol., 14, 2019
8G5N
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BU of 8g5n by Molmil
Cryo-EM structure of the Guide loop Engagement Complex (VI) of Human Mitochondrial DNA Polymerase Gamma
Descriptor: DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ...
Authors:Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D.
Deposit date:2023-02-13
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:Structural basis for DNA proofreading.
Nat Commun, 14, 2023
8G5K
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BU of 8g5k by Molmil
Cryo-EM structure of the Wedge Alignment Complex (VIII) of Human Mitochondrial DNA Polymerase Gamma
Descriptor: DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ...
Authors:Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D.
Deposit date:2023-02-13
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for DNA proofreading.
Nat Commun, 14, 2023
8G5I
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BU of 8g5i by Molmil
Cryo-EM structure of the Mismatch Sensing Complex (I) of Human Mitochondrial DNA Polymerase Gamma
Descriptor: DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ...
Authors:Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D.
Deposit date:2023-02-13
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Structural basis for DNA proofreading.
Nat Commun, 14, 2023
8G5M
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BU of 8g5m by Molmil
Cryo-EM structure of the Mismatch Locking Complex (III) of Human Mitochondrial DNA Polymerase Gamma
Descriptor: DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ...
Authors:Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D.
Deposit date:2023-02-13
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Structural basis for DNA proofreading.
Nat Commun, 14, 2023
8G5J
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BU of 8g5j by Molmil
Cryo-EM structure of the Mismatch Uncoupling Complex (II) of Human Mitochondrial DNA Polymerase Gamma
Descriptor: DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ...
Authors:Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D.
Deposit date:2023-02-13
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (2.63 Å)
Cite:Structural basis for DNA proofreading.
Nat Commun, 14, 2023

223532

数据于2024-08-07公开中

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