5G1T
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![BU of 5g1t by Molmil](/molmil-images/mine/5g1t) | S. enterica HisA mutant dup13-15, D10G | Descriptor: | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, PHOSPHATE ION | Authors: | Guo, X, Soderholm, A, Newton, M, Nasvall, J, Andersson, D, Patrick, W, Selmer, M. | Deposit date: | 2016-03-30 | Release date: | 2017-04-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5G2I
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![BU of 5g2i by Molmil](/molmil-images/mine/5g2i) | S. enterica HisA mutant Dup13-15(VVR) | Descriptor: | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, PHOSPHATE ION, SODIUM ION | Authors: | Guo, X, Soderholm, A, Newton, M, Nasvall, J, Duarte, F, Andersson, D, Patrick, W, Selmer, M. | Deposit date: | 2016-04-08 | Release date: | 2017-04-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.601 Å) | Cite: | Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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7YZX
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![BU of 7yzx by Molmil](/molmil-images/mine/7yzx) | ScpA from Streptococcus pyogenes, D783A mutant. | Descriptor: | C5a peptidase, CALCIUM ION, MALONIC ACID, ... | Authors: | Kagawa, T.F, Cooney, J.C, Jain, M. | Deposit date: | 2022-02-21 | Release date: | 2022-08-31 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | X-ray diffraction data for the C5a-peptidase mutant with modified activity and specificity. Data Brief, 46, 2023
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1VC4
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![BU of 1vc4 by Molmil](/molmil-images/mine/1vc4) | Crystal Structure of Indole-3-Glycerol Phosphate Synthase (TrpC) from Thermus Thermophilus At 1.8 A Resolution | Descriptor: | ACETIC ACID, GLYCEROL, Indole-3-Glycerol Phosphate Synthase, ... | Authors: | Bagautdinov, B, Tahirov, T.H, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-03-04 | Release date: | 2004-03-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of indole-3-glycerol phosphate synthase from Thermus thermophilus HB8: implications for thermal stability. Acta Crystallogr.,Sect.D, 67, 2011
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2HLV
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![BU of 2hlv by Molmil](/molmil-images/mine/2hlv) | Bovine Odorant Binding Protein deswapped triple mutant | Descriptor: | 3,6-BIS(METHYLENE)DECANOIC ACID, GLYCEROL, Odorant-binding protein | Authors: | Spinelli, S, Tegoni, M, Cambillau, C. | Deposit date: | 2006-07-10 | Release date: | 2008-03-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Deswapping bovine odorant binding protein. Biochim.Biophys.Acta, 1784, 2008
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4TM9
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![BU of 4tm9 by Molmil](/molmil-images/mine/4tm9) | |
8J4A
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![BU of 8j4a by Molmil](/molmil-images/mine/8j4a) | Crystal structure of OY phytoplasma SAP05 in complex with AtRPN10 | Descriptor: | 26S proteasome non-ATPase regulatory subunit 4 homolog, Sequence-variable mosaic (SVM) signal sequence domain-containing protein | Authors: | Dong, C, Yan, X, Yuan, X. | Deposit date: | 2023-04-19 | Release date: | 2024-02-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Molecular basis of SAP05-mediated ubiquitin-independent proteasomal degradation of transcription factors. Nat Commun, 15, 2024
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4K4R
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8JTL
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![BU of 8jtl by Molmil](/molmil-images/mine/8jtl) | Structure of OY phytoplasma SAP05 binding with AtRpn10 | Descriptor: | 26S proteasome non-ATPase regulatory subunit 4 homolog, Sequence-variable mosaic (SVM) signal sequence domain-containing protein | Authors: | Du, Y.X, Zhang, L.Y, Zheng, Q.Y. | Deposit date: | 2023-06-22 | Release date: | 2023-07-12 | Last modified: | 2024-07-17 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structure basis for recognition of plant Rpn10 by phytoplasma SAP05 in ubiquitin-independent protein degradation. Iscience, 27, 2024
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8JTK
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![BU of 8jtk by Molmil](/molmil-images/mine/8jtk) | Structure of AYWB phytoplasma SAP05 recognizing AtRpn10 | Descriptor: | 26S proteasome non-ATPase regulatory subunit 4 homolog, Sequence-variable mosaic (SVM) signal sequence domain-containing protein | Authors: | Du, Y.X, Zhang, L.Y, Zheng, Q.Y. | Deposit date: | 2023-06-22 | Release date: | 2023-07-19 | Last modified: | 2024-07-17 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Structure basis for recognition of plant Rpn10 by phytoplasma SAP05 in ubiquitin-independent protein degradation. Iscience, 27, 2024
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4K4Q
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![BU of 4k4q by Molmil](/molmil-images/mine/4k4q) | TL-3 inhibited Trp6Ala HIV Protease with 3-bromo-2,6-dimethoxybenzoic acid bound in flap site | Descriptor: | 3-bromo-2,6-dimethoxybenzoic acid, BETA-MERCAPTOETHANOL, DIMETHYL SULFOXIDE, ... | Authors: | Tiefenbrunn, T, Stout, C.D. | Deposit date: | 2013-04-12 | Release date: | 2013-09-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystallographic Fragment-Based Drug Discovery: Use of a Brominated Fragment Library Targeting HIV Protease. Chem.Biol.Drug Des., 83, 2014
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4K4P
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![BU of 4k4p by Molmil](/molmil-images/mine/4k4p) | TL-3 inhibited Trp6Ala HIV Protease | Descriptor: | HIV-1 protease, NITRATE ION, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate | Authors: | Tiefenbrunn, T, Stout, C.D. | Deposit date: | 2013-04-12 | Release date: | 2013-09-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Crystallographic Fragment-Based Drug Discovery: Use of a Brominated Fragment Library Targeting HIV Protease. Chem.Biol.Drug Des., 83, 2014
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4BTH
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![BU of 4bth by Molmil](/molmil-images/mine/4bth) | The LeuA146Trp,PheB24Tyr Double Mutant of the Quorum Quenching N-acyl Homoserine Lactone Acylase PvdQ Has an Altered Substrate Specificity Towards Small Acyl Chains | Descriptor: | ACYL-HOMOSERINE LACTONE ACYLASE PVDQ SUBUNIT ALPHA, ACYL-HOMOSERINE LACTONE ACYLASE PVDQ SUBUNIT BETA, GLYCEROL | Authors: | Koch, G, Nadal-Jimenez, P, Reis, C.R, Muntendam, R, Bokhove, M, Melillo, E, Dijkstra, B.W, Cool, R.H, Quax, W.J. | Deposit date: | 2013-06-18 | Release date: | 2014-01-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Reducing Virulence of the Human Pathogen Burkholderia by Altering the Substrate Specificity of the Quorum-Quenching Acylase Pvdq Proc.Natl.Acad.Sci.USA, 111, 2014
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5KJA
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![BU of 5kja by Molmil](/molmil-images/mine/5kja) | Synechocystis apocarotenoid oxygenase (ACO) mutant - Trp149Ala | Descriptor: | Apocarotenoid-15,15'-oxygenase, CHLORIDE ION, FE (II) ION | Authors: | Sui, X, Kiser, P.D, Palczewski, K. | Deposit date: | 2016-06-18 | Release date: | 2016-08-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Key Residues for Catalytic Function and Metal Coordination in a Carotenoid Cleavage Dioxygenase. J.Biol.Chem., 291, 2016
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5A2L
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![BU of 5a2l by Molmil](/molmil-images/mine/5a2l) | Crystal structure of scFv-SM3 in complex with APD-CGalNAc-RP | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose, MODIFIED ANTIGEN TN, ... | Authors: | Martinez-Saez, N, Castro-Lopez, J, Valero-Gonzalez, J, Madariaga, D, Companon, I, Somovilla, V.J, Salvado, M, Asensio, J.L, Jimenez-Barbero, J, Avenoza, A, Busto, J.H, Bernardes, G.J.L, Peregrina, J.M, Hurtado-Guerrero, R, Corzana, F. | Deposit date: | 2015-05-20 | Release date: | 2015-06-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an Anti-Muc1 Antibody. Angew.Chem.Int.Ed.Engl., 54, 2015
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5A2I
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![BU of 5a2i by Molmil](/molmil-images/mine/5a2i) | Crystal structure of scFv-SM3 in complex with APD-SGalNAc-RP | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose, ANTIGEN TN, ... | Authors: | Martinez-Saez, N, Castro-Lopez, J, Valero-Gonzalez, J, Madariaga, D, Companon, I, Somovilla, V.J, Salvado, M, Asensio, J.L, Jimenez-Barbero, J, Avenoza, A, Busto, J.H, Bernardes, G.J.L, Peregrina, J.M, Hurtado-Guerrero, R, Corzana, F. | Deposit date: | 2015-05-20 | Release date: | 2015-06-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an Anti-Muc1 Antibody. Angew.Chem.Int.Ed.Engl., 54, 2015
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6C7H
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5A2K
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![BU of 5a2k by Molmil](/molmil-images/mine/5a2k) | Crystal structure of scFv-SM3 in complex with APD-TGalNAc-RP | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose, ANTIGEN TN, ... | Authors: | Martinez-Saez, N, Castro-Lopez, J, Valero-Gonzalez, J, Madariaga, D, Companon, I, Somovilla, V.J, Salvado, M, Asensio, J.L, Jimenez-Barbero, J, Avenoza, A, Busto, J.H, Bernardes, G.J.L, Peregrina, J.M, Hurtado-Guerrero, R, Corzana, F. | Deposit date: | 2015-05-20 | Release date: | 2015-06-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an Anti-Muc1 Antibody. Angew.Chem.Int.Ed.Engl., 54, 2015
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8EKG
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![BU of 8ekg by Molmil](/molmil-images/mine/8ekg) | MHETase variant Thr159Val, Met192Tyr, Tyr252Phe, Tyr503Trp | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Saunders, J.W, Frkic, R.L, Jackson, C.J. | Deposit date: | 2022-09-20 | Release date: | 2023-10-18 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Increasing the Soluble Expression and Whole-Cell Activity of the Plastic-Degrading Enzyme MHETase through Consensus Design. Biochemistry, 63, 2024
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5U0U
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5UBS
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![BU of 5ubs by Molmil](/molmil-images/mine/5ubs) | Solution NMR Structure of NERD-S, a natively folded pentamutant of the B1 domain of streptococcal protein G (GB1) with a solvent-exposed Trp43 | Descriptor: | Immunoglobulin G-binding protein G | Authors: | Damry, A.M, Davey, J.A, Goto, N.K, Chica, R.A. | Deposit date: | 2016-12-21 | Release date: | 2017-08-23 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Rational design of proteins that exchange on functional timescales. Nat. Chem. Biol., 13, 2017
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5U0R
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![BU of 5u0r by Molmil](/molmil-images/mine/5u0r) | |
5TPL
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![BU of 5tpl by Molmil](/molmil-images/mine/5tpl) | |
5TPP
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![BU of 5tpp by Molmil](/molmil-images/mine/5tpp) | |
8QIJ
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![BU of 8qij by Molmil](/molmil-images/mine/8qij) | Crystallographic Structure of a Salicylate Synthase from M. abscessus (Mab-SaS) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Cassetta, A, Covaceuszach, S, Tomaiuolo, M, Meneghetti, F, Villa, S, Mori, M, Chiarelli, L.R, Mangiatordi, G.F. | Deposit date: | 2023-09-12 | Release date: | 2024-01-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.073 Å) | Cite: | Structural basis for specific inhibition of salicylate synthase from Mycobacterium abscessus. Eur.J.Med.Chem., 265, 2024
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