5A2K

Crystal structure of scFv-SM3 in complex with APD-TGalNAc-RP

Summary for 5A2K

Entry DOI	10.2210/pdb5a2k/pdb
Related	5A2I 5A2J 5A2L
Descriptor	IG LAMBDA-1 CHAIN V REGION S43, ANTIGEN TN, THR IS COVALENTLY BOUND TO GALNAC, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	immune system, glycopeptides, antibodies, molecular recognition, conformation analysis, fusion protein
Biological source	MUS MUSCULUS (HOUSE MOUSE) More
Total number of polymer chains	2
Total formula weight	26992.66
Authors	Martinez-Saez, N.,Castro-Lopez, J.,Valero-Gonzalez, J.,Madariaga, D.,Companon, I.,Somovilla, V.J.,Salvado, M.,Asensio, J.L.,Jimenez-Barbero, J.,Avenoza, A.,Busto, J.H.,Bernardes, G.J.L.,Peregrina, J.M.,Hurtado-Guerrero, R.,Corzana, F. (deposition date: 2015-05-20, release date: 2015-06-03, Last modification date: 2024-01-10)
Primary citation	Martinez-Saez, N.,Castro-Lopez, J.,Valero-Gonzalez, J.,Madariaga, D.,Companon, I.,Somovilla, V.J.,Salvado, M.,Asensio, J.L.,Jimenez-Barbero, J.,Avenoza, A.,Busto, J.H.,Bernardes, G.J.L.,Peregrina, J.M.,Hurtado-Guerrero, R.,Corzana, F. Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an Anti-Muc1 Antibody. Angew.Chem.Int.Ed.Engl., 54:9830-, 2015 Cited by PubMed: 26118689 DOI: 10.1002/ANIE.201502813 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation