5U0U

Crystal Structure of DH270.1 (unliganded, single-chain Fv) from the DH270 Broadly Neutralizing N332-glycan Dependent Lineage

Summary for 5U0U

• Entry DOI: 10.2210/pdb5u0u/pdb
• Related: 5TPL 5TPP 5TQA 5TRP 5U0R 5U15
• EMDB information: 8507
• Descriptor: DH270.1 single-chain variable fragment (1 entity in total)
• Functional Keywords: single-chain variable fragment, hiv-1, antibody, immune system
• Biological source: Homo sapiens
• Total number of polymer chains: 4
• Total formula weight: 109203.92

Authors

Fera, D.,Harrison, S.C. (deposition date: 2016-11-27, release date: 2017-03-15, Last modification date: 2023-10-04)

• Primary citation: Bonsignori, M.,Kreider, E.F.,Fera, D.,Meyerhoff, R.R.,Bradley, T.,Wiehe, K.,Alam, S.M.,Aussedat, B.,Walkowicz, W.E.,Hwang, K.K.,Saunders, K.O.,Zhang, R.,Gladden, M.A.,Monroe, A.,Kumar, A.,Xia, S.M.,Cooper, M.,Louder, M.K.,McKee, K.,Bailer, R.T.,Pier, B.W.,Jette, C.A.,Kelsoe, G.,Williams, W.B.,Morris, L.,Kappes, J.,Wagh, K.,Kamanga, G.,Cohen, M.S.,Hraber, P.T.,Montefiori, D.C.,Trama, A.,Liao, H.X.,Kepler, T.B.,Moody, M.A.,Gao, F.,Danishefsky, S.J.,Mascola, J.R.,Shaw, G.M.,Hahn, B.H.,Harrison, S.C.,Korber, B.T.,Haynes, B.F.; Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.; Sci Transl Med, 9:-, 2017; PubMed: 28298420; DOI: 10.1126/scitranslmed.aai7514

Experimental method

X-RAY DIFFRACTION (3.428 Å)