5A2L

Crystal structure of scFv-SM3 in complex with APD-CGalNAc-RP

Summary for 5A2L

• Entry DOI: 10.2210/pdb5a2l/pdb
• Related: 5A2I 5A2J 5A2K
• Descriptor: SCFV-SM3, MODIFIED ANTIGEN TN, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: immune system, peptide binding protein, glycopeptides, antibodies, molecular recognition, conformation analysis, fusion protein
• Biological source: MUS MUSCULUS (HOUSE MOUSE); More
• Total number of polymer chains: 2
• Total formula weight: 26870.56

Authors

Martinez-Saez, N.,Castro-Lopez, J.,Valero-Gonzalez, J.,Madariaga, D.,Companon, I.,Somovilla, V.J.,Salvado, M.,Asensio, J.L.,Jimenez-Barbero, J.,Avenoza, A.,Busto, J.H.,Bernardes, G.J.L.,Peregrina, J.M.,Hurtado-Guerrero, R.,Corzana, F. (deposition date: 2015-05-20, release date: 2015-06-03, Last modification date: 2024-01-10)

• Primary citation: Martinez-Saez, N.,Castro-Lopez, J.,Valero-Gonzalez, J.,Madariaga, D.,Companon, I.,Somovilla, V.J.,Salvado, M.,Asensio, J.L.,Jimenez-Barbero, J.,Avenoza, A.,Busto, J.H.,Bernardes, G.J.L.,Peregrina, J.M.,Hurtado-Guerrero, R.,Corzana, F.; Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an Anti-Muc1 Antibody.; Angew.Chem.Int.Ed.Engl., 54:9830-, 2015; PubMed: 26118689; DOI: 10.1002/ANIE.201502813

Experimental method

X-RAY DIFFRACTION (1.79 Å)