5A2L
Crystal structure of scFv-SM3 in complex with APD-CGalNAc-RP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | SCFV-SM3 | polymer | 244 | 25742.3 | 1 | UniProt (P01801) UniProt (P01727) Pfam (PF07686) | MUS MUSCULUS (HOUSE MOUSE) | |
| 2 | B (P) | MODIFIED ANTIGEN TN | polymer | 6 | 658.7 | 1 | HOMO SAPIENS | ||
| 3 | C, D, E, F (H) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 4 | G (P) | 2-acetamido-2-deoxy-alpha-D-galactopyranose | non-polymer | 221.2 | 1 | Chemie (A2G) | |||
| 5 | H, I (H, P) | water | water | 18.0 | 113 | Chemie (HOH) |
Sequence modifications
H: 6 - 113 (UniProt: P01801)
H: 1003 - 1107 (UniProt: P01727)
| PDB | External Database | Details |
|---|---|---|
| Gln 1 | - | cloning artifact |
| Val 2 | - | cloning artifact |
| Gln 3 | - | cloning artifact |
| Leu 4 | - | cloning artifact |
| Gln 5 | - | cloning artifact |
| Gly 94 | - | insertion |
| Val 95 | Thr 100 | conflict |
| Gln 97 | - | insertion |
| Thr 108 | Leu 110 | conflict |
| Ser 114 | - | linker |
| Ser 115 | - | linker |
| Gly 116 | - | linker |
| Gly 117 | - | linker |
| Gly 118 | - | linker |
| Gly 119 | - | linker |
| Ser 120 | - | linker |
| Gly 121 | - | linker |
| Gly 122 | - | linker |
| Gly 123 | - | linker |
| Gly 124 | - | linker |
| Gly 125 | - | linker |
| Ser 126 | - | linker |
| Ser 127 | - | linker |
| Gly 128 | - | linker |
| Ser 129 | - | linker |
| Ser 130 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Asp 1002 | Gln 20 | conflict |
| Ile 1003 | Ala 21 | conflict |
| Ala 1078 | Thr 98 | conflict |
| Ile 1085 | Met 106 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 26401.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 469.5 | |
| All* | Total formula weight | 26870.6 |
