2GO7
 
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2NOV
 | | Breakage-reunion domain of S.pneumoniae topo IV: crystal structure of a gram-positive quinolone target | | Descriptor: | DNA topoisomerase 4 subunit A | | Authors: | Laponogov, I, Veselkov, D.A, Sohi, M.K, Pan, X.S, Achari, A, Yang, C, Ferrara, J.D, Fisher, L.M, Sanderson, M.R. | | Deposit date: | 2006-10-26 | | Release date: | 2006-11-14 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.67 Å) | | Cite: | Breakage-Reunion Domain of Streptococcus pneumoniae Topoisomerase IV: Crystal Structure of a Gram-Positive Quinolone Target.
PLoS ONE, 2, 2007
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2HQ0
 | | Structure of RafE from Streptococcus pneumoniae | | Descriptor: | ACETATE ION, SODIUM ION, Sugar ABC transporter, ... | | Authors: | Paterson, N.G, Riboldi-Tunnicliffe, A, Mitchell, T.J, Isaacs, N.W. | | Deposit date: | 2006-07-18 | | Release date: | 2007-07-31 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | High resolution crystal structures of RafE from Streptococcus pneumoniae
To be Published
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2I0M
 | | Crystal structure of the phosphate transport system regulatory protein PhoU from Streptococcus pneumoniae | | Descriptor: | Phosphate transport system protein phoU, ZINC ION | | Authors: | Zhang, R, Li, H, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2006-08-10 | | Release date: | 2006-09-19 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of the phosphate transport system regulatory protein PhoU from Streptococcus pneumoniae
To be Published, 2006
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2YP6
 | | Crystal structure of the pneumoccocal exposed lipoprotein thioredoxin sp_1000 (Etrx2) from Streptococcus pneumoniae strain TIGR4 in complex with Cyclofos 3 TM | | Descriptor: | 3-Cyclohexyl-1-Propylphosphocholine, MALONATE ION, THIOREDOXIN FAMILY PROTEIN | | Authors: | Bartual, S.G, Shalek, M, Abdullah, M.R, Jensch, I, Asmat, T.M, Petruschka, L, Pribyl, T, Hermoso, J.A, Hammerschmidt, S. | | Deposit date: | 2012-10-29 | | Release date: | 2013-10-30 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.767 Å) | | Cite: | Molecular Architecture of Streptococcus Pneumoniae Surface Thioredoxin-Fold Lipoproteins Crucial for Extracellular Oxidative Stress Resistance and Maintenance of Virulence.
Embo Mol.Med., 5, 2013
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1UUP
 | | Crystal Structure of A Dimeric Form of Streptococcal Pyrogenic Exotoxin A (SpeA1). | | Descriptor: | EXOTOXIN TYPE A, ZINC ION | | Authors: | Baker, M.D, Gendlina, I, Collins, C.M, Acharya, K.R. | | Deposit date: | 2004-01-08 | | Release date: | 2004-08-12 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal Structure of a Dimeric Form of Streptococcal Pyrogenic Exotoxin a (Spea1)
Protein Sci., 13, 2004
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1XF1
 | | Structure of C5a peptidase- a key virulence factor from Streptococcus | | Descriptor: | ACETATE ION, C5a peptidase, CALCIUM ION, ... | | Authors: | Brown, C.K, Gu, Z.Y, Cleary, P.P, Matsuka, Y, Olmstead, S, Ohlendorf, D.H, Earhart, C.A. | | Deposit date: | 2004-09-13 | | Release date: | 2005-11-22 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of the streptococcal cell wall C5a peptidase
Proc.Natl.Acad.Sci.Usa, 102, 2005
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2CAX
 | | STRUCTURAL BASIS FOR COOPERATIVE BINDING OF RIBBON-HELIX-HELIX REPRESSOR OMEGA TO MUTATED DIRECT DNA HEPTAD REPEATS | | Descriptor: | 5'-D(*CP*TP*TP*GP*TP*GP*AP*CP*TP*TP *GP*TP*GP*AP*TP*TP*CP*G)-3', 5'-D(*GP*AP*AP*TP*CP*AP*CP*AP*AP*AP *TP*CP*AP*CP*AP*AP*G)-3', 5'-D(*GP*AP*AP*TP*CP*AP*CP*AP*AP*GP *TP*CP*AP*CP*AP*AP*GP*C)-3', ... | | Authors: | Weihofen, W.A, Cicek, A, Pratto, F, Alonso, J.C, Saenger, W. | | Deposit date: | 2005-12-23 | | Release date: | 2006-03-15 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structures of Omega Repressors Bound to Direct and Inverted DNA Repeats Explain Modulation of Transcription.
Nucleic Acids Res., 34, 2006
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2W1J
 | | CRYSTAL STRUCTURE OF SORTASE C-1 (SRTC-1) from Streptococcus pneumoniae | | Descriptor: | GLYCEROL, PUTATIVE SORTASE | | Authors: | Manzano, C, Contreras-Martel, C, El Mortaji, L, Izore, T, Fenel, D, Vernet, T, Schoehn, G, Di Guilmi, A.M, Dessen, A. | | Deposit date: | 2008-10-17 | | Release date: | 2008-12-23 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.24 Å) | | Cite: | Sortase-Mediated Pilus Fiber Biogenesis in Streptococcus Pneumoniae.
Structure, 16, 2008
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2JTC
 | | 3D structure and backbone dynamics of SPE B | | Descriptor: | Streptopain | | Authors: | Chuang, W, Wang, C, Houng, H, Chen, C, Wang, P. | | Deposit date: | 2007-07-26 | | Release date: | 2008-08-26 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure and backbone dynamics of streptopain: insight into diverse substrate specificity.
J.Biol.Chem., 284, 2009
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1R5J
 | | Crystal Structure of a Phosphotransacetylase from Streptococcus pyogenes | | Descriptor: | putative phosphotransacetylase | | Authors: | Xu, Q.S, Shin, D.H, Pufan, R, Yokota, H, Kim, R, Kim, S.H, Berkeley Structural Genomics Center (BSGC) | | Deposit date: | 2003-10-10 | | Release date: | 2004-04-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of a phosphotransacetylase from Streptococcus pyogenes.
Proteins, 55, 2004
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2FLI
 | | The crystal structure of D-ribulose 5-phosphate 3-epimerase from Streptococus pyogenes complexed with D-xylitol 5-phosphate | | Descriptor: | D-XYLITOL-5-PHOSPHATE, ZINC ION, ribulose-phosphate 3-epimerase | | Authors: | Fedorov, A.A, Fedorov, E.V, Akana, J, Gerlt, J.A, Almo, S.C. | | Deposit date: | 2006-01-06 | | Release date: | 2006-03-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | d-Ribulose 5-Phosphate 3-Epimerase: Functional and Structural Relationships to Members of the Ribulose-Phosphate Binding (beta/alpha)(8)-Barrel Superfamily(,).
Biochemistry, 45, 2006
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2WMG
 | | Crystal structure of the catalytic module of a family 98 glycoside hydrolase from Streptococcus pneumoniae TIGR4 (Sp4GH98) in complex with the LewisY pentasaccharide blood group antigen. | | Descriptor: | FUCOLECTIN-RELATED PROTEIN, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Higgins, M.A, Whitworth, G.E, El Warry, N, Randriantsoa, M, Samain, E, Burke, R.D, Vocadlo, D.J, Boraston, A.B. | | Deposit date: | 2009-06-30 | | Release date: | 2009-07-14 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Differential Recognition and Hydrolysis of Host Carbohydrate-Antigens by Streptococcus Pneumoniae Family 98 Glycoside Hydrolases.
J.Biol.Chem., 284, 2009
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2WWD
 | | 3D-structure of the modular autolysin LytC from Streptococcus pneumoniae in complex with pneummococcal peptidoglycan fragment | | Descriptor: | 1,4-BETA-N-ACETYLMURAMIDASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-alpha-muramic acid, ALANINE, ... | | Authors: | Perez-Dorado, I, Sanles, R, Hermoso, J.A, Gonzalez, A, Garcia, A, Garcia, P, Garcia, J.L. | | Deposit date: | 2009-10-22 | | Release date: | 2010-04-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Insights Into Pneumococcal Fratricide from the Crystal Structures of the Modular Killing Factor Lytc.
Nat.Struct.Mol.Biol., 17, 2010
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1YDF
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1Z72
 | | Structure of a putative transcriptional regulator from Streptococcus pneumoniae | | Descriptor: | ACETIC ACID, MAGNESIUM ION, transcriptional regulator, ... | | Authors: | Cuff, M.E, Zhou, M, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2005-03-23 | | Release date: | 2005-05-17 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structure of a putative transcriptional regulator from Streptococcus pneumoniae
To be Published
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2XGR
 | | extracellular endonuclease | | Descriptor: | DI(HYDROXYETHYL)ETHER, SPD1 NUCLEASE | | Authors: | Korczynska, J.E, Turkenburg, J.P, Taylor, E.J. | | Deposit date: | 2010-06-07 | | Release date: | 2011-07-20 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The Structural Characterization of a Prophage-Encoded Extracellular DNase from Streptococcus Pyogenes.
Nucleic Acids Res., 40, 2012
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2YLA
 | | INHIBITION OF THE PNEUMOCOCCAL VIRULENCE FACTOR STRH AND MOLECULAR INSIGHTS INTO N-GLYCAN RECOGNITION AND HYDROLYSIS | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Pluvinage, B, Higgins, M.A, Abbott, D.W, Robb, C, Dalia, A.B, Deng, L, Weiser, J.N, Parsons, T.B, Fairbanks, A.J, Vocadlo, D.J, Boraston, A.B. | | Deposit date: | 2011-06-01 | | Release date: | 2011-09-07 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Inhibition of the Pneumococcal Virulence Factor Strh and Molecular Insights Into N-Glycan Recognition and Hydrolysis.
Structure, 19, 2011
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2I7R
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2YA5
 | | Crystal structure of Streptococcus pneumoniae NanA (TIGR4) in complex with sialic acid | | Descriptor: | CHLORIDE ION, FORMIC ACID, N-acetyl-alpha-neuraminic acid, ... | | Authors: | Gut, H, Xu, G, Taylor, G.L, Walsh, M.A. | | Deposit date: | 2011-02-18 | | Release date: | 2011-04-27 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Basis for Streptococcus Pneumoniae Nana Inhibition by Influenza Antivirals Zanamivir and Oseltamivir Carboxylate.
J.Mol.Biol., 409, 2011
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2I58
 | | Crystal Structure of RafE from Streptococcus pneumoniae complexed with raffinose | | Descriptor: | CHLORIDE ION, Sugar ABC transporter, sugar-binding protein, ... | | Authors: | Paterson, N.G, Riboldi-Tunnicliffe, A, Mitchell, T.J, Isaacs, N.W. | | Deposit date: | 2006-08-24 | | Release date: | 2007-08-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of apo and bound forms of RafE from Streptococcus pneumoniae
To be Published
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2IBO
 | | X-ray Crystal Structure of Protein SP2199 from Streptococcus pneumoniae. Northeast Structural Genomics Consortium Target SpR31 | | Descriptor: | Hypothetical protein SP2199 | | Authors: | Seetharaman, J, Abashidze, M, Forouhar, F, Shastry, R, Conover, K, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2006-09-11 | | Release date: | 2006-10-03 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of the hypothetical protein SP2199 from Streptococcus pneumoniae, Northeast structural genomics target SpR31
To be Published
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2L3A
 | | Solution NMR structure of homodimer protein SP_0782 (7-79) from Streptococcus pneumoniae Northeast Structural Genomics Consortium Target SpR104 . | | Descriptor: | Uncharacterized protein | | Authors: | Yang, Y, Ramelot, T.A, Lee, D, Ciccosanti, C, Hamilton, K, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2010-09-10 | | Release date: | 2010-11-10 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of hepothetical homodimer protein SP_0782 (7-79) from Streptococcus pneumoniae, Northeast Structural Genomics Consortium Target SpR104
To be Published
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2YA7
 | | Crystal structure of Streptococcus pneumoniae NanA (TIGR4) in complex with Zanamivir | | Descriptor: | CHLORIDE ION, NEURAMINIDASE A, ZANAMIVIR | | Authors: | Gut, H, Xu, G, Taylor, G.L, Walsh, M.A. | | Deposit date: | 2011-02-18 | | Release date: | 2011-04-27 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Structural Basis for Streptococcus Pneumoniae Nana Inhibition by Influenza Antivirals Zanamivir and Oseltamivir Carboxylate.
J.Mol.Biol., 409, 2011
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2HFB
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