2YA7

Crystal structure of Streptococcus pneumoniae NanA (TIGR4) in complex with Zanamivir

Summary for 2YA7

Entry DOI	10.2210/pdb2ya7/pdb
Related	2YA4 2YA5 2YA6 2YA8
Descriptor	NEURAMINIDASE A, ZANAMIVIR, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	hydrolase, sialidase
Biological source	STREPTOCOCCUS PNEUMONIAE
Total number of polymer chains	4
Total formula weight	222857.79
Authors	Gut, H.,Xu, G.,Taylor, G.L.,Walsh, M.A. (deposition date: 2011-02-18, release date: 2011-04-27, Last modification date: 2020-09-02)
Primary citation	Gut, H.,Xu, G.,Taylor, G.L.,Walsh, M.A. Structural Basis for Streptococcus Pneumoniae Nana Inhibition by Influenza Antivirals Zanamivir and Oseltamivir Carboxylate. J.Mol.Biol., 409:496-, 2011 Cited by PubMed: 21514303 DOI: 10.1016/J.JMB.2011.04.016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.89 Å)

Structure validation