8PF0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8pf0 by Molmil](/molmil-images/mine/8pf0) | Diubiquitin-derived artificial binding protein (Affilin) variant Af1 specific to oncofetal fibronectin | Descriptor: | Affilin variant Af1 (77405), COPPER (II) ION, IMIDAZOLE | Authors: | Parthier, C, Katzschmann, A, Fiedler, E, Haupts, U, Reimann, A. | Deposit date: | 2023-06-15 | Release date: | 2024-06-26 | Last modified: | 2024-08-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Ubiquitin-derived artificial binding proteins targeting oncofetal fibronectin reveal scaffold plasticity by beta-strand slippage. Commun Biol, 7, 2024
|
|
2NB1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2nb1 by Molmil](/molmil-images/mine/2nb1) | P63/p73 hetero-tetramerisation domain | Descriptor: | Tumor protein 63, Tumor protein p73 | Authors: | Gebel, J, Buchner, L, Loehr, F.M, Luh, L.M, Coutandin, D, Guentert, P, Doetsch, V. | Deposit date: | 2016-01-19 | Release date: | 2016-12-07 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Mechanism of TAp73 inhibition by Delta Np63 and structural basis of p63/p73 hetero-tetramerization. Cell Death Differ., 23, 2016
|
|
8PEX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8pex by Molmil](/molmil-images/mine/8pex) | Rho P167L-ATPgS-Psu complex I | Descriptor: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Polarity suppression protein, ... | Authors: | Gjorgjevikj, D, Wahl, M.C, Hilal, T, Loll, B. | Deposit date: | 2023-06-15 | Release date: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Rho P167L-ATPgS-Psu complex I To Be Published
|
|
3K8X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3k8x by Molmil](/molmil-images/mine/3k8x) | Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in complex with tepraloxydim | Descriptor: | (5S)-2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-3-hydroxy-5-(tetrahydro-2H-pyran-4-yl)cyclohex-2-en-1-one, Acetyl-CoA carboxylase | Authors: | Xiang, S, Callaghan, M.M, Watson, K.G, Tong, L. | Deposit date: | 2009-10-15 | Release date: | 2009-12-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A different mechanism for the inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase by tepraloxydim. Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
7Q9H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7q9h by Molmil](/molmil-images/mine/7q9h) | Peptide LLKAVAEKQ in complex with human cathepsin V C25A mutant | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Cathepsin L2, ... | Authors: | Loboda, J, Sosnowski, P, Tusar, L, Vidmar, R, Vizovisek, M, Horvat, J, Kosec, G, Impens, F, Demol, H, Turk, B, Gevaert, K, Turk, D. | Deposit date: | 2021-11-12 | Release date: | 2022-11-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Proteomic data and structure analysis combined reveal interplay of structural rigidity and flexibility on selectivity of cysteine cathepsins. Commun Biol, 6, 2023
|
|
5MBY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mby by Molmil](/molmil-images/mine/5mby) | Crystal Structure of Arg184Gln mutant of Human Prolidase with Mn ions and GlyPro ligand | Descriptor: | GLYCEROL, GLYCINE, HYDROXIDE ION, ... | Authors: | Wilk, P, Piwowarczyk, R, Mueller, U, Dobbek, H, Weiss, M.S. | Deposit date: | 2016-11-09 | Release date: | 2017-12-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural basis for prolidase deficiency disease mechanisms. FEBS J., 285, 2018
|
|
8PEU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8peu by Molmil](/molmil-images/mine/8peu) | Rho-ATPgS-Psu complex I | Descriptor: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Polarity suppression protein, ... | Authors: | Gjorgjevikj, D, Wahl, M.C, Hilal, T, Loll, B. | Deposit date: | 2023-06-15 | Release date: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Rho-ATPgS-Psu complex I To Be Published
|
|
5MED
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5med by Molmil](/molmil-images/mine/5med) | Cyanothece lipoxygenase 2 (CspLOX2) | Descriptor: | 1,3-PROPANDIOL, 1,4-BUTANEDIOL, 1-BUTANOL, ... | Authors: | Newie, J, Neumann, P, Werner, M, Mata, R.A, Ficner, R, Feussner, I. | Deposit date: | 2016-11-14 | Release date: | 2017-05-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Lipoxygenase 2 from Cyanothece sp. controls dioxygen insertion by steric shielding and substrate fixation. Sci Rep, 7, 2017
|
|
3KAN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3kan by Molmil](/molmil-images/mine/3kan) | |
7BFX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7bfx by Molmil](/molmil-images/mine/7bfx) | deoxyxylose nucleic acid hairpin | Descriptor: | dXyNA (5'-D(*(XA)P*(XG)P*(XC)P*(XA)P*(XA)P*(XT)P*(XC)P*(XC)P*(XC)P*(XC)P*(XC)P*(XC)P*(XG)P*(XG)P*(XA)P*(XT)P*(XT)P*(XG)P*(XC)P*T)-3') | Authors: | Mattelaer, C.-A, Mohitosh, M, Smets, L, Maiti, M, Schepers, G, Mattelaer, H.-P, Rosemeyer, H, Herdewijn, P, Lescrinier, E. | Deposit date: | 2021-01-05 | Release date: | 2021-01-27 | Last modified: | 2024-01-31 | Method: | SOLUTION NMR | Cite: | Stable Hairpin Structures Formed by Xylose-Based Nucleic Acids. Chembiochem, 22, 2021
|
|
7TQB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7tqb by Molmil](/molmil-images/mine/7tqb) | |
7Q8G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7q8g by Molmil](/molmil-images/mine/7q8g) | Peptide ALAASS in complex with human cathepsin V C25S mutant | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ALAASS Peptide, CHLORIDE ION, ... | Authors: | Loboda, J, Sosnowski, P, Tusar, L, Vidmar, R, Vizovisek, M, Horvat, J, Kosec, G, Impens, F, Demol, H, Turk, B, Gevaert, K, Turk, D. | Deposit date: | 2021-11-11 | Release date: | 2022-11-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Proteomic data and structure analysis combined reveal interplay of structural rigidity and flexibility on selectivity of cysteine cathepsins. Commun Biol, 6, 2023
|
|
5MDM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mdm by Molmil](/molmil-images/mine/5mdm) | Structural intermediates in the fusion associated transition of vesiculovirus glycoprotein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Baquero, E, Albertini, A.A, Gaudin, Y, Bressanelli, S. | Deposit date: | 2016-11-11 | Release date: | 2016-12-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.998 Å) | Cite: | Structural intermediates in the fusion-associated transition of vesiculovirus glycoprotein. EMBO J., 36, 2017
|
|
2I9B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2i9b by Molmil](/molmil-images/mine/2i9b) | Crystal structure of ATF-urokinase receptor complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Urokinase plasminogen activator surface receptor, ... | Authors: | Lubkowski, J, Barinka, C. | Deposit date: | 2006-09-05 | Release date: | 2007-01-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of interaction between urokinase-type plasminogen activator and its receptor. J.Mol.Biol., 363, 2006
|
|
7JSG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jsg by Molmil](/molmil-images/mine/7jsg) | Adeno-Associated Virus 2 Rep68 HD-Heptamer-ssDNA with ATPgS | Descriptor: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Protein Rep68 | Authors: | Escalante, C.R. | Deposit date: | 2020-08-14 | Release date: | 2020-12-09 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (5.2 Å) | Cite: | The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA+ machine that can switch between oligomeric states. Nucleic Acids Res., 48, 2020
|
|
8PEQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8peq by Molmil](/molmil-images/mine/8peq) | Complex of diubiquitin-derived artificial binding protein (Affilin) variant Af2 with its target oncofetal fibronectin (fragment 7B8) | Descriptor: | Affilin variant Af2, Fibronectin, SULFATE ION | Authors: | Parthier, C, Katzschmann, A, Fiedler, E, Haupts, U, Reimann, A. | Deposit date: | 2023-06-14 | Release date: | 2024-06-26 | Last modified: | 2024-08-14 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Ubiquitin-derived artificial binding proteins targeting oncofetal fibronectin reveal scaffold plasticity by beta-strand slippage. Commun Biol, 7, 2024
|
|
8PJG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8pjg by Molmil](/molmil-images/mine/8pjg) | F11 TCR in complex with Human Leukocyte Antigen class II allotype DR1 presenting P11T->R modified influenza A virus haemagglutinin (HA)306-318 PKYVKQNTLKLAR | Descriptor: | 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, HLA class II histocompatibility antigen, ... | Authors: | MacLachlan, B.J, Wall, A, Greenshields-Watson, A.L, Cole, D.K, Rizkallah, P.J, Godkin, A.J. | Deposit date: | 2023-06-23 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4 + T cell activation. Cell Rep, 43, 2024
|
|
7Q8J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7q8j by Molmil](/molmil-images/mine/7q8j) | Peptide IILKEK in complex with human cathepsin V C25S mutant | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Cathepsin L2, EYS Peptide, ... | Authors: | Loboda, J, Sosnowski, P, Tusar, L, Vidmar, R, Vizovisek, M, Horvat, J, Kosec, G, Impens, F, Demol, H, Turk, B, Gevaert, K, Turk, D. | Deposit date: | 2021-11-11 | Release date: | 2022-11-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Proteomic data and structure analysis combined reveal interplay of structural rigidity and flexibility on selectivity of cysteine cathepsins. Commun Biol, 6, 2023
|
|
2XK8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xk8 by Molmil](/molmil-images/mine/2xk8) | Structure of Nek2 bound to aminopyrazine compound 15 | Descriptor: | 4-[3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl]-2-methoxybenzoic acid, CHLORIDE ION, SERINE/THREONINE-PROTEIN KINASE NEK2 | Authors: | Mas-Droux, C, Bayliss, R. | Deposit date: | 2010-07-07 | Release date: | 2010-10-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Aminopyrazine Inhibitors Binding to an Unusual Inactive Conformation of the Mitotic Kinase Nek2: Sar and Structural Characterization. J.Med.Chem., 53, 2010
|
|
7Q8K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7q8k by Molmil](/molmil-images/mine/7q8k) | Peptide LLKVAL in complex with human cathepsin V C25S mutant | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Cathepsin L2, ... | Authors: | Loboda, J, Sosnowski, P, Tusar, L, Vidmar, R, Vizovisek, M, Horvat, J, Kosec, G, Impens, F, Demol, H, Turk, B, Gevaert, K, Turk, D. | Deposit date: | 2021-11-11 | Release date: | 2022-11-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Proteomic data and structure analysis combined reveal interplay of structural rigidity and flexibility on selectivity of cysteine cathepsins. Commun Biol, 6, 2023
|
|
8PEY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8pey by Molmil](/molmil-images/mine/8pey) | Rho P167L-ATPgS-Psu complex II | Descriptor: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Polarity suppression protein, ... | Authors: | Gjorgjevikj, D, Wahl, M.C, Hilal, T, Loll, B. | Deposit date: | 2023-06-15 | Release date: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Rho P167L-ATPgS-Psu complex II To Be Published
|
|
3J6M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3j6m by Molmil](/molmil-images/mine/3j6m) | Kinetic and Structural Analysis of Coxsackievirus B3 Receptor Interactions and Formation of the A-particle | Descriptor: | Coxsackievirus and adenovirus receptor | Authors: | Organtini, L.J, Makhov, A.M, Conway, J.F, Hafenstein, S, Carson, S.D. | Deposit date: | 2014-03-19 | Release date: | 2014-04-09 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Kinetic and structural analysis of coxsackievirus b3 receptor interactions and formation of the a-particle. J.Virol., 88, 2014
|
|
2I06
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2i06 by Molmil](/molmil-images/mine/2i06) | Escherichia Coli Replication Terminator Protein (Tus) Complexed With DNA- Locked form | Descriptor: | 5'-D(*T*TP*AP*GP*TP*TP*AP*CP*AP*AP*CP*AP*TP*AP*CP*T)-3', 5'-D(*TP*G*AP*TP*AP*TP*GP*TP*TP*GP*TP*AP*AP*CP*TP*A)-3', DNA replication terminus site-binding protein, ... | Authors: | Oakley, A.J, Mulcair, M.D, Schaeffer, P.M, Dixon, N.E. | Deposit date: | 2006-08-10 | Release date: | 2007-08-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Polarity of Termination of DNA Replication in E. coli. To be Published
|
|
2XKN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xkn by Molmil](/molmil-images/mine/2xkn) | Crystal structure of the Fab fragment of the anti-EGFR antibody 7A7 | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ANTI-EGFR ANTIBODY 7A7 | Authors: | Talavera, A, Mackenzie, J, Friemann, R, Krengel, U. | Deposit date: | 2010-07-09 | Release date: | 2011-06-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure of the Fab Fragment of the Anti-Murine Egfr Antibody 7A7 and Exploration of its Receptor Binding Site. Mol.Immunol., 48, 2011
|
|
3J6O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3j6o by Molmil](/molmil-images/mine/3j6o) | Kinetic and Structural Analysis of Coxsackievirus B3 Receptor Interactions and Formation of the A-particle | Descriptor: | Coxsackie and adenovirus receptor | Authors: | Organtini, L.J, Makhov, A.M, Conway, J.F, Hafenstein, S, Carson, S.D. | Deposit date: | 2014-03-19 | Release date: | 2014-04-09 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Kinetic and structural analysis of coxsackievirus b3 receptor interactions and formation of the a-particle. J.Virol., 88, 2014
|
|