8PF0
Diubiquitin-derived artificial binding protein (Affilin) variant Af1 specific to oncofetal fibronectin
Summary for 8PF0
Entry DOI | 10.2210/pdb8pf0/pdb |
Descriptor | Affilin variant Af1 (77405), COPPER (II) ION, IMIDAZOLE, ... (4 entities in total) |
Functional Keywords | extra domain b, edb, oncofetal fibronectin, ubiquitin, diubiqutin, affilin, beta strand register shift, strand slippage, scaffold, artificial binding protein, plasticity, directed evolution, de novo protein |
Biological source | Homo sapiens |
Total number of polymer chains | 1 |
Total formula weight | 17921.46 |
Authors | Parthier, C.,Katzschmann, A.,Fiedler, E.,Haupts, U.,Reimann, A. (deposition date: 2023-06-15, release date: 2024-06-26) |
Primary citation | Katzschmann, A.,Fiedler, E.,Haupts, U.,Reimann, A.,Settele, F.,Gloser-Braeunig, M.,Parthier, C. Ubiquitin-derived artificial binding proteins targeting oncofetal fibronectin reveal scaffold plasticity by beta-strand slippage to be published, |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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