7Q8K
Peptide LLKVAL in complex with human cathepsin V C25S mutant
This is a non-PDB format compatible entry.
Summary for 7Q8K
Entry DOI | 10.2210/pdb7q8k/pdb |
Descriptor | Cathepsin L2, LLKVAL Peptide, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (6 entities in total) |
Functional Keywords | cathepsinv, peptidyl substrate, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 50318.31 |
Authors | Loboda, J.,Sosnowski, P.,Tusar, L.,Vidmar, R.,Vizovisek, M.,Horvat, J.,Kosec, G.,Impens, F.,Demol, H.,Turk, B.,Gevaert, K.,Turk, D. (deposition date: 2021-11-11, release date: 2022-11-23, Last modification date: 2024-02-07) |
Primary citation | Tusar, L.,Loboda, J.,Impens, F.,Sosnowski, P.,Van Quickelberghe, E.,Vidmar, R.,Demol, H.,Sedeyn, K.,Saelens, X.,Vizovisek, M.,Mihelic, M.,Fonovic, M.,Horvat, J.,Kosec, G.,Turk, B.,Gevaert, K.,Turk, D. Proteomic data and structure analysis combined reveal interplay of structural rigidity and flexibility on selectivity of cysteine cathepsins. Commun Biol, 6:450-450, 2023 Cited by PubMed: 37095140DOI: 10.1038/s42003-023-04772-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.74 Å) |
Structure validation
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