2XKN

Crystal structure of the Fab fragment of the anti-EGFR antibody 7A7

Summary for 2XKN

• Entry DOI: 10.2210/pdb2xkn/pdb
• Descriptor: ANTI-EGFR ANTIBODY 7A7, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... (4 entities in total)
• Functional Keywords: immune system, immunoglobulin
• Biological source: MUS MUSCULUS (HOUSE MOUSE); More
• Total number of polymer chains: 4
• Total formula weight: 96921.93

Authors

Talavera, A.,Mackenzie, J.,Friemann, R.,Krengel, U. (deposition date: 2010-07-09, release date: 2011-06-15, Last modification date: 2023-12-20)

• Primary citation: Talavera, A.,Mackenzie, J.,Garrido, G.,Friemann, R.,Lopez-Requena, A.,Moreno, E.,Krengel, U.; Structure of the Fab Fragment of the Anti-Murine Egfr Antibody 7A7 and Exploration of its Receptor Binding Site.; Mol.Immunol., 48:1578-, 2011; PubMed: 21592580; DOI: 10.1016/J.MOLIMM.2011.03.016

Experimental method

X-RAY DIFFRACTION (1.4 Å)