7Q9H

Peptide LLKAVAEKQ in complex with human cathepsin V C25A mutant

This is a non-PDB format compatible entry.

Summary for 7Q9H

• Entry DOI: 10.2210/pdb7q9h/pdb
• Descriptor: Cathepsin L2, LLKAVAEKQ Peptide, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: cathepsinv, peptidyl substrate, hydrolase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 52549.17

Authors

Loboda, J.,Sosnowski, P.,Tusar, L.,Vidmar, R.,Vizovisek, M.,Horvat, J.,Kosec, G.,Impens, F.,Demol, H.,Turk, B.,Gevaert, K.,Turk, D. (deposition date: 2021-11-12, release date: 2022-11-23, Last modification date: 2024-02-07)

• Primary citation: Tusar, L.,Loboda, J.,Impens, F.,Sosnowski, P.,Van Quickelberghe, E.,Vidmar, R.,Demol, H.,Sedeyn, K.,Saelens, X.,Vizovisek, M.,Mihelic, M.,Fonovic, M.,Horvat, J.,Kosec, G.,Turk, B.,Gevaert, K.,Turk, D.; Proteomic data and structure analysis combined reveal interplay of structural rigidity and flexibility on selectivity of cysteine cathepsins.; Commun Biol, 6:450-450, 2023; PubMed: 37095140; DOI: 10.1038/s42003-023-04772-8

Experimental method

X-RAY DIFFRACTION (1.4 Å)