6FWR
 
 | | Structure of DinG in complex with ssDNA | | Descriptor: | ATP-dependent DNA helicase DinG, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), IRON/SULFUR CLUSTER | | Authors: | Cheng, K, Wigley, D.B. | | Deposit date: | 2018-03-07 | | Release date: | 2018-12-19 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | DNA translocation mechanism of an XPD family helicase.
Elife, 7, 2018
|
|
8ENK
 | |
6FSZ
 | | Structure of the nuclear RNA exosome | | Descriptor: | ATP-dependent RNA helicase DOB1, Exosome complex component CSL4, Exosome complex component MTR3, ... | | Authors: | Schuller, J.M, Falk, S, Conti, E. | | Deposit date: | 2018-02-20 | | Release date: | 2018-03-21 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Structure of the nuclear exosome captured on a maturing preribosome.
Science, 360, 2018
|
|
6QID
 | | Crystal structure of DEAH-box ATPase Prp43-S387A | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Hamann, F, Ficner, R, Enders, M. | | Deposit date: | 2019-01-18 | | Release date: | 2019-03-06 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.204 Å) | | Cite: | Structural basis for RNA translocation by DEAH-box ATPases.
Nucleic Acids Res., 47, 2019
|
|
7OS2
 | | Cryo-EM structure of Brr2 in complex with Jab1/MPN and C9ORF78 | | Descriptor: | Pre-mRNA-processing-splicing factor 8, Telomere length and silencing protein 1 homolog, U5 small nuclear ribonucleoprotein 200 kDa helicase | | Authors: | Bergfort, A, Hilal, T, Weber, G, Wahl, M.C. | | Deposit date: | 2021-06-07 | | Release date: | 2022-02-23 | | Last modified: | 2024-09-25 | | Method: | ELECTRON MICROSCOPY (2.76 Å) | | Cite: | The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling.
Nucleic Acids Res., 50, 2022
|
|
7OS1
 | | Cryo-EM structure of Brr2 in complex with Fbp21 | | Descriptor: | U5 small nuclear ribonucleoprotein 200 kDa helicase, WW domain-binding protein 4 | | Authors: | Bergfort, A, Hilal, T, Weber, G, Wahl, M.C. | | Deposit date: | 2021-06-07 | | Release date: | 2022-02-23 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling.
Nucleic Acids Res., 50, 2022
|
|
6RM9
 | | Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP | | Descriptor: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Hamann, F, Neumann, P, Ficner, R. | | Deposit date: | 2019-05-06 | | Release date: | 2020-02-05 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6RMB
 | | Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative mRNA splicing factor, ... | | Authors: | Hamann, F, Neumann, P, Ficner, R. | | Deposit date: | 2019-05-06 | | Release date: | 2020-02-05 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6RO1
 | | X-ray crystal structure of the MTR4 NVL complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Exosome RNA helicase MTR4, ... | | Authors: | Lingaraju, M, Langer, L.M, Basquin, J, Falk, S, Conti, E. | | Deposit date: | 2019-05-10 | | Release date: | 2019-07-03 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.07 Å) | | Cite: | The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs.
Nat Commun, 10, 2019
|
|
7PX3
 | | Structure of U5 snRNP assembly and recycling factor TSSC4 in complex with BRR2 and Jab1 domain of PRPF8 | | Descriptor: | Pre-mRNA-processing-splicing factor 8, Protein TSSC4, U5 small nuclear ribonucleoprotein 200 kDa helicase | | Authors: | Bergfort, A, Kuropka, B, Ilik, I.A, Freund, C, Aktas, T, Hilal, T, Weber, G, Wahl, M.C. | | Deposit date: | 2021-10-07 | | Release date: | 2022-01-26 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.05 Å) | | Cite: | The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling.
Nucleic Acids Res., 50, 2022
|
|
6RM8
 | | Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP | | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | | Authors: | Hamann, F, Neumann, P, Ficner, R. | | Deposit date: | 2019-05-06 | | Release date: | 2020-02-05 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
7PQ0
 | | Crystal structure of the Burkholderia Lethal Factor 1 (BLF1) C94S inactive mutant in complex with human eIF4A - Crystal form B | | Descriptor: | Burkholderia Lethal Factor 1 (BLF1), Eukaryotic initiation factor 4A-I | | Authors: | Mobbs, G.W, Aziz, A.A, Dix, S.R, Blackburn, G.M, Sedelnikova, S.E, Minshull, T.C, Dickman, M.J, Baker, P.J, Nathan, S, Firdaus-Raih, M, Rice, D.W. | | Deposit date: | 2021-09-15 | | Release date: | 2022-04-13 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Molecular basis of specificity and deamidation of eIF4A by Burkholderia Lethal Factor 1.
Commun Biol, 5, 2022
|
|
7PPZ
 | | Crystal structure of the Burkholderia Lethal Factor 1 (BLF1) C94S inactive mutant in complex with human eIF4A - Crystal form A | | Descriptor: | Burkholderia Lethal Factor 1 (BLF1), Eukaryotic initiation factor 4A-I | | Authors: | Mobbs, G.W, Aziz, A.A, Dix, S.R, Blackburn, G.M, Sedelnikova, S.E, Minshull, T.C, Dickman, M.J, Baker, P.J, Nathan, S, Firdaus-Raih, M, Rice, D.W. | | Deposit date: | 2021-09-15 | | Release date: | 2022-04-13 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.52 Å) | | Cite: | Molecular basis of specificity and deamidation of eIF4A by Burkholderia Lethal Factor 1.
Commun Biol, 5, 2022
|
|
6S8Q
 | | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 | | Descriptor: | Pre-mRNA-processing-splicing factor 8, SULFATE ION, U5 small nuclear ribonucleoprotein 200 kDa helicase | | Authors: | Santos, K.F, Vester, K, Wahl, M.C. | | Deposit date: | 2019-07-10 | | Release date: | 2020-01-22 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.391 Å) | | Cite: | The inactive C-terminal cassette of the dual-cassette RNA helicase BRR2 both stimulates and inhibits the activity of the N-terminal helicase unit.
J.Biol.Chem., 295, 2020
|
|
6S9I
 | |
6SH7
 | |
7PLI
 | | DEAD-box helicase DbpA bound to single stranded RNA and ADP/BeF3 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DbpA, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Wurm, J.P. | | Deposit date: | 2021-08-31 | | Release date: | 2022-09-07 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis for RNA-duplex unwinding by the DEAD-box helicase DbpA.
Rna, 29, 2023
|
|
6SH6
 | | Crystal structure of the human DEAH-helicase DHX15 in complex with the NKRF G-patch bound to ADP | | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Jonas, S, Studer, M.K, Ivanovic, L. | | Deposit date: | 2019-08-05 | | Release date: | 2020-04-22 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural basis for DEAH-helicase activation by G-patch proteins.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
7PMQ
 | |
7PMM
 | |
6S8O
 | | Human Brr2 Helicase Region M641C/A1582C | | Descriptor: | U5 small nuclear ribonucleoprotein 200 kDa helicase | | Authors: | Vester, K, Santos, K.F, Wahl, M.C. | | Deposit date: | 2019-07-10 | | Release date: | 2020-01-22 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (3.172 Å) | | Cite: | The inactive C-terminal cassette of the dual-cassette RNA helicase BRR2 both stimulates and inhibits the activity of the N-terminal helicase unit.
J.Biol.Chem., 295, 2020
|
|
6RMA
 | | Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... | | Authors: | Hamann, F, Neumann, P, Ficner, R. | | Deposit date: | 2019-05-06 | | Release date: | 2020-02-05 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6QWS
 | |
6QV3
 | | Crystal structure of the Ski2 RNA-helicase Brr2 from Chaetomium thermophilum bound to ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ... | | Authors: | Absmeier, E, Santos, K.F, Wahl, M.C. | | Deposit date: | 2019-03-01 | | Release date: | 2020-01-15 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Molecular Mechanism Underlying Inhibition of Intrinsic ATPase Activity in a Ski2-like RNA Helicase.
Structure, 28, 2020
|
|
6QV4
 | | Crystal structure of the Ski2 RNA-helicase Brr2 from Chaetomium thermophilum bound to ATP-gamma-S | | Descriptor: | ACETATE ION, MANGANESE (II) ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Absmeier, E, Santos, K.F, Wahl, M.C. | | Deposit date: | 2019-03-01 | | Release date: | 2020-01-15 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Molecular Mechanism Underlying Inhibition of Intrinsic ATPase Activity in a Ski2-like RNA Helicase.
Structure, 28, 2020
|
|
