6SH6

Crystal structure of the human DEAH-helicase DHX15 in complex with the NKRF G-patch bound to ADP

Summary for 6SH6

Entry DOI	10.2210/pdb6sh6/pdb
Descriptor	Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15, NF-kappa-B-repressing factor, ADENOSINE-5'-DIPHOSPHATE, ... (6 entities in total)
Functional Keywords	g-patch, deah helicase, dexh helicase, hydrolase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	87002.79
Authors	Jonas, S.,Studer, M.K.,Ivanovic, L. (deposition date: 2019-08-05, release date: 2020-04-22, Last modification date: 2024-01-24)
Primary citation	Studer, M.K.,Ivanovic, L.,Weber, M.E.,Marti, S.,Jonas, S. Structural basis for DEAH-helicase activation by G-patch proteins. Proc.Natl.Acad.Sci.USA, 117:7159-7170, 2020 Cited by PubMed: 32179686 DOI: 10.1073/pnas.1913880117 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation