6SH6
Crystal structure of the human DEAH-helicase DHX15 in complex with the NKRF G-patch bound to ADP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 | polymer | 689 | 79063.8 | 1 | UniProt (O43143) Pfam (PF00270) Pfam (PF00271) Pfam (PF04408) Pfam (PF21010) Pfam (PF07717) In PDB | Homo sapiens (Human) | ATP-dependent RNA helicase #46,DEAH box protein 15 |
2 | B | NF-kappa-B-repressing factor | polymer | 67 | 7425.5 | 1 | UniProt (O15226) Pfam (PF01585) In PDB | Homo sapiens (Human) | NFkB-repressing factor,Protein ITBA4,Transcription factor NRF |
3 | A | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
5 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
6 | water | water | 18.0 | 299 | Chemie (HOH) |
Sequence modifications
A: 113 - 795 (UniProt: O43143)
B: 541 - 603 (UniProt: O15226)
PDB | External Database | Details |
---|---|---|
Gly 107 | - | expression tag |
Pro 108 | - | expression tag |
His 109 | - | expression tag |
Met 110 | - | expression tag |
Leu 111 | - | expression tag |
Glu 112 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 537 | - | expression tag |
Pro 538 | - | expression tag |
His 539 | - | expression tag |
Met 540 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 86489.2 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 513.6 | |
All* | Total formula weight | 87002.8 |