7OS1

Cryo-EM structure of Brr2 in complex with Fbp21

Summary for 7OS1

• Entry DOI: 10.2210/pdb7os1/pdb
• EMDB information: 13045
• Descriptor: U5 small nuclear ribonucleoprotein 200 kDa helicase, WW domain-binding protein 4 (2 entities in total)
• Functional Keywords: mrna splicing, spliceosomal assembly, splicing regulation, brr2 helicase, splicing
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 218994.56

Authors

Bergfort, A.,Hilal, T.,Weber, G.,Wahl, M.C. (deposition date: 2021-06-07, release date: 2022-02-23, Last modification date: 2024-07-17)

• Primary citation: Bergfort, A.,Hilal, T.,Kuropka, B.,Ilik, I.A.,Weber, G.,Aktas, T.,Freund, C.,Wahl, M.C.; The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling.; Nucleic Acids Res., 50:2938-2958, 2022; PubMed: 35188580; DOI: 10.1093/nar/gkac087

Experimental method

ELECTRON MICROSCOPY (3.3 Å)