6QE1
| P38 alpha complex with AR117046 | Descriptor: | 1-[5-~{tert}-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[(1~{S},4~{R})-4-[(3-propan-2-yl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)oxy]-1,2,3,4-tetrahydronaphthalen-1-yl]urea, 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine, Mitogen-activated protein kinase 14 | Authors: | Brown, D.G, Hurley, C, Irving, S.L. | Deposit date: | 2019-01-03 | Release date: | 2020-01-29 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | P38 alpha complex with AR117045 and AR117046 To Be Published
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1KFW
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2Z4Q
| Crystal structure of a murine antibody FAB 528 | Descriptor: | CADMIUM ION, CHLORIDE ION, anti egfr antibody fab, ... | Authors: | Nakanishi, T, Tsumoto, K, Asano, R, Kondo, H, Kumagai, I. | Deposit date: | 2007-06-22 | Release date: | 2007-10-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Thermodynamic consequences of mutations in vernier zone residues of a humanized anti-human epidermal growth factor receptor murine antibody, 528 J.Biol.Chem., 283, 2008
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2Z6B
| Crystal Structure Analysis of (gp27-gp5)3 conjugated with Fe(III) protoporphyrin | Descriptor: | 1-ETHYL-PYRROLIDINE-2,5-DIONE, Baseplate structural protein Gp27, Tail-associated lysozyme | Authors: | Koshiyama, T, Yokoi, N, Ueno, T, Kanamaru, S, Nagano, S, Shiro, Y, Arisaka, F, Watanabe, Y. | Deposit date: | 2007-07-28 | Release date: | 2008-04-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | Molecular design of heteroprotein assemblies providing a bionanocup as a chemical reactor. Small, 4, 2008
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3JBP
| Cryo-electron microscopy reconstruction of the Plasmodium falciparum 80S ribosome bound to E-tRNA | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein eS1, ... | Authors: | Sun, M, Li, W, Blomqvist, K, Das, S, Hashem, Y, Dvorin, J.D, Frank, J. | Deposit date: | 2015-09-16 | Release date: | 2015-10-14 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (6.7 Å) | Cite: | Dynamical features of the Plasmodium falciparum ribosome during translation. Nucleic Acids Res., 43, 2015
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8H77
| Hsp90-AhR-p23-XAP2 complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, Aryl hydrocarbon receptor, ... | Authors: | Wen, Z.L, Zhai, Y.J, Zhu, Y, Sun, F. | Deposit date: | 2022-10-19 | Release date: | 2023-01-04 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure of the cytosolic AhR complex. Structure, 31, 2023
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8R3L
| Influenza A/H7N9 polymerase in pre-initiation state, intermediate conformation (I) with PB2-C(I), ENDO(T), and Pol II pS5 CTD peptide mimic bound in site 1A/2A | Descriptor: | 3' vRNA end (51-mer vRNA loop), Polymerase acidic protein, Polymerase basic protein 2, ... | Authors: | Arragain, B, Cusack, S. | Deposit date: | 2023-11-09 | Release date: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15, 2024
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1KLF
| FIMH ADHESIN-FIMC CHAPERONE COMPLEX WITH D-MANNOSE | Descriptor: | CHAPERONE PROTEIN FIMC, FIMH PROTEIN, alpha-D-mannopyranose | Authors: | Hung, C.S, Bouckaert, J. | Deposit date: | 2001-12-11 | Release date: | 2002-06-05 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection. Mol.Microbiol., 44, 2002
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1KNZ
| Recognition of the rotavirus mRNA 3' consensus by an asymmetric NSP3 homodimer | Descriptor: | 5'-R(*UP*GP*AP*CP*C)-3', Nonstructural RNA-binding Protein 34 | Authors: | Deo, R.C, Groft, C.M, Rajashankar, K.R, Burley, S.K. | Deposit date: | 2001-12-19 | Release date: | 2002-01-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Recognition of the rotavirus mRNA 3' consensus by an asymmetric NSP3 homodimer. Cell(Cambridge,Mass.), 108, 2002
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1KC8
| Co-crystal Structure of Blasticidin S Bound to the 50S Ribosomal Subunit | Descriptor: | 23S RRNA, 5S RRNA, BLASTICIDIN S, ... | Authors: | Hansen, J.L, Ban, N, Nissen, P, Moore, P.B, Steitz, T.A. | Deposit date: | 2001-11-07 | Release date: | 2003-07-22 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of
the Large Ribosomal Subunit J.Mol.Biol., 330, 2003
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5XZF
| Vitamin D receptor with a synthetic ligand ADRO1 | Descriptor: | (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,6S)-6-(1-adamantyl)-6-oxidanyl-hex-4-yn-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol, FORMIC ACID, Mediator of RNA polymerase II transcription subunit 1, ... | Authors: | Otero, R, Numoto, N, Ikura, T, Yamada, S, Mourino, A, Makishima, M, Ito, N. | Deposit date: | 2017-07-12 | Release date: | 2018-07-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | 25 S-Adamantyl-23-yne-26,27-dinor-1 alpha ,25-dihydroxyvitamin D3: Synthesis, Tissue Selective Biological Activities, and X-ray Crystal Structural Analysis of Its Vitamin D Receptor Complex. J. Med. Chem., 61, 2018
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1KHZ
| Structure of the ADPR-ase in complex with AMPCPR and Mg | Descriptor: | ADP-ribose pyrophosphatase, ALPHA-BETA METHYLENE ADP-RIBOSE, CHLORIDE ION, ... | Authors: | Gabelli, S.B, Bianchet, M.A, Bessman, M.J, Amzel, L.M. | Deposit date: | 2001-12-01 | Release date: | 2002-10-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Mechanism of the Escherichia coli ADP-ribose pyrophosphatase, a Nudix hydrolase. Biochemistry, 41, 2002
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8BBG
| Structure of the IFT-A complex; anterograde IFT-A train model | Descriptor: | Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 140 homolog, Intraflagellar transport protein 43 homolog, ... | Authors: | Hesketh, S.J, Mukhopadhyay, A.G, Nakamura, D, Toropova, K, Roberts, A.J. | Deposit date: | 2022-10-12 | Release date: | 2022-12-21 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | IFT-A structure reveals carriages for membrane protein transport into cilia. Cell, 185, 2022
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2ZBG
| Calcium pump crystal structure with bound AlF4 and TG in the absence of calcium | Descriptor: | MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, ... | Authors: | Toyoshima, C, Ogawa, H, Norimatsu, Y. | Deposit date: | 2007-10-20 | Release date: | 2007-12-11 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | How processing of aspartylphosphate is coupled to lumenal gating of the ion pathway in the calcium pump Proc.Natl.Acad.Sci.Usa, 104, 2007
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2Z3P
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1KD1
| Co-crystal Structure of Spiramycin bound to the 50S Ribosomal Subunit of Haloarcula marismortui | Descriptor: | 23S RRNA, 5S RRNA, CADMIUM ION, ... | Authors: | Hansen, J.L, Ippolito, J.A, Ban, N, Nissen, P, Moore, P.B, Steitz, T.A. | Deposit date: | 2001-11-12 | Release date: | 2002-07-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The structures of four macrolide antibiotics bound to the large ribosomal subunit. Mol.Cell, 10, 2002
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8BBE
| Structure of the IFT-A complex; IFT-A2 module | Descriptor: | Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 43 homolog, SNAP-tag,Tetratricopeptide repeat protein 21B, ... | Authors: | Hesketh, S.J, Mukhopadhyay, A.G, Nakamura, D, Toropova, K, Roberts, A.J. | Deposit date: | 2022-10-12 | Release date: | 2022-12-21 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | IFT-A structure reveals carriages for membrane protein transport into cilia. Cell, 185, 2022
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1L9A
| CRYSTAL STRUCTURE OF SRP19 IN COMPLEX WITH THE S DOMAIN OF SIGNAL RECOGNITION PARTICLE RNA | Descriptor: | MAGNESIUM ION, METHYL MERCURY ION, SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN, ... | Authors: | Oubridge, C, Kuglstatter, A, Jovine, L, Nagai, K. | Deposit date: | 2002-03-22 | Release date: | 2002-06-28 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of SRP19 in complex with the S domain of SRP RNA and its implication for the assembly of the signal recognition particle. Mol.Cell, 9, 2002
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2RHI
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2RHY
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8BVM
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5Y41
| Crystal Structure of LIGAND-BOUND NURR1-LBD | Descriptor: | (13E,15S)-15-hydroxy-9-oxoprosta-10,13-dien-1-oic acid, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Sreekanth, R, Lescar, J, Yoon, H.S. | Deposit date: | 2017-07-31 | Release date: | 2018-12-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | PGE1 and PGA1 bind to Nurr1 and activate its transcriptional function. Nat.Chem.Biol., 2020
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5Y7X
| Human Peroxisome proliferator-activated receptor (PPAR) delta in complexed with a potent and selective agonist | Descriptor: | 2-[2-methyl-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-selenazol-5-yl]methylsulfanyl]phenoxy]ethanoic acid, CHLORIDE ION, POTASSIUM ION, ... | Authors: | Kim, H.L, Chin, J.W, Cho, S.J, Song, J.Y, Yoon, H.S, Bae, J.H. | Deposit date: | 2017-08-18 | Release date: | 2018-08-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.699 Å) | Cite: | Design, synthesis, and the X-ray co-crystal structure of Highly Potent, Selective, and Orally Bioavailable, Novel Peroxisome Proliferator-Activated Receptor delta Agonists To Be Published
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1LL5
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8BVJ
| Hfq-Crc-estA translation repression complex | Descriptor: | Catabolite repression control protein, RNA-binding protein Hfq, estA mRNA | Authors: | Dendooven, T, Luisi, B.F. | Deposit date: | 2022-12-04 | Release date: | 2023-01-25 | Last modified: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Translational regulation by Hfq-Crc assemblies emerges from polymorphic ribonucleoprotein folding. Embo J., 42, 2023
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