6QE1

P38 alpha complex with AR117046

Summary for 6QE1

• Entry DOI: 10.2210/pdb6qe1/pdb
• Related: 6QDZ
• Descriptor: Mitogen-activated protein kinase 14, 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine, 1-[5-~{tert}-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[(1~{S},4~{R})-4-[(3-propan-2-yl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)oxy]-1,2,3,4-tetrahydronaphthalen-1-yl]urea, ... (4 entities in total)
• Functional Keywords: inhibitor, complex, kinase, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 42322.28

Authors

Brown, D.G.,Hurley, C.,Irving, S.L. (deposition date: 2019-01-03, release date: 2020-01-29)

• Primary citation: Brown, D.G.,Irving, S.L.; P38 alpha complex with AR117045 and AR117046; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)