8BBG

Structure of the IFT-A complex; anterograde IFT-A train model

Summary for 8BBG

• Entry DOI: 10.2210/pdb8bbg/pdb
• Related: 8BBE 8BBF
• EMDB information: 15954 15955 4304
• Descriptor: WD repeat-containing protein 19, Intraflagellar transport protein 140 homolog, Intraflagellar transport protein 122 homolog, ... (6 entities in total)
• Functional Keywords: cilia, intraflagellar transport, membrane protein import, complex, transport protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 791281.04

Authors

Hesketh, S.J.,Mukhopadhyay, A.G.,Nakamura, D.,Toropova, K.,Roberts, A.J. (deposition date: 2022-10-12, release date: 2022-12-21, Last modification date: 2023-01-04)

• Primary citation: Hesketh, S.J.,Mukhopadhyay, A.G.,Nakamura, D.,Toropova, K.,Roberts, A.J.; IFT-A structure reveals carriages for membrane protein transport into cilia.; Cell, 185:4971-, 2022; PubMed: 36462505; DOI: 10.1016/j.cell.2022.11.010

Experimental method

ELECTRON MICROSCOPY (3.5 Å)