2Z4Q

Crystal structure of a murine antibody FAB 528

Summary for 2Z4Q

Related1WT5
Descriptoranti egfr antibody fab, light chain, anti egfr antibody fab, heavy chain, CADMIUM ION, ... (5 entities in total)
Functional Keywordsimmune system
Biological sourceMus musculus (house mouse)
Total number of polymer chains2
Total molecular weight48136.6
Authors
Nakanishi, T.,Tsumoto, K.,Asano, R.,Kondo, H.,Kumagai, I. (deposition date: 2007-06-22, release date: 2007-10-30, Last modification date: 2011-07-13)
Primary citation
Makabe, K.,Nakanishi, T.,Tsumoto, K.,Tanaka, Y.,Kondo, H.,Umetsu, M.,Sone, Y.,Asano, R.,Kumagai, I.
Thermodynamic consequences of mutations in vernier zone residues of a humanized anti-human epidermal growth factor receptor murine antibody, 528
J.Biol.Chem., 283:1156-1166, 2008
PubMed: 17947238 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M706190200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.3 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.226110.5%3.4%3.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2z4q
no rotation
Molmil generated image of 2z4q
rotated about x axis by 90°
Molmil generated image of 2z4q
rotated about y axis by 90°