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3TEG
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BU of 3teg by Molmil
Bacterial and Eukaryotic Phenylalanyl-tRNA Synthetases Catalyze Misaminoacylation of tRNAPhe with 3,4-Dihydroxy-L-Phenylalanine (L-Dopa)
Descriptor: 3,4-DIHYDROXYPHENYLALANINE, Phenylalanyl-tRNA synthetase, mitochondrial
Authors:Moor, N, Klipcan, L, Safro, M.
Deposit date:2011-08-14
Release date:2011-11-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2044 Å)
Cite:Bacterial and Eukaryotic Phenylalanyl-tRNA Synthetases Catalyze Misaminoacylation of tRNA(Phe) with 3,4-Dihydroxy-L-Phenylalanine.
Chem.Biol., 18, 2011
3CDM
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BU of 3cdm by Molmil
Structural adaptation and conservation in quadruplex-drug recognition
Descriptor: 2,7-bis[3-(dimethylamino)propyl]-4,9-bis[(3-hydroxypropyl)amino]benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetrone, DNA (5'-D(*DT*DAP*DGP*DGP*DGP*DTP*DTP*DAP*DGP*DGP*DGP*DTP*DTP*DAP*DGP*DGP*DGP*DTP*DTP*DAP*DGP*DGP*DG)-3'), POTASSIUM ION
Authors:Parkinson, G.N, Neidle, S.
Deposit date:2008-02-27
Release date:2008-09-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Topology conservation and loop flexibility in quadruplex-drug recognition: crystal structures of inter- and intramolecular telomeric DNA quadruplex-drug complexes
J.Mol.Biol., 381, 2008
4XCZ
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BU of 4xcz by Molmil
X-ray structure of the N-formyltransferase QdtF from Providencia alcalifaciens in complex with TDP-Qui3n and N5-THF
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid, ...
Authors:Thoden, J.B, Woodford, C.R, Holden, H.M.
Deposit date:2014-12-18
Release date:2015-01-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:New Role for the Ankyrin Repeat Revealed by a Study of the N-Formyltransferase from Providencia alcalifaciens.
Biochemistry, 54, 2015
1VZB
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BU of 1vzb by Molmil
L. CASEI THYMIDYLATE SYNTHASE MUTANT E60Q BINARY COMPLEX WITH DUMP
Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE
Authors:Birdsall, D.L, Finer-Moore, J, Stroud, R.M.
Deposit date:1996-09-18
Release date:1997-03-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The separate effects of E60Q in Lactobacillus casei thymidylate synthase delineate between mechanisms for formation of intermediates in catalysis.
Protein Eng., 11, 1998
3CCO
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BU of 3cco by Molmil
Structural adaptation and conservation in quadruplex-drug recognition
Descriptor: 2,7-bis[3-(dimethylamino)propyl]-4,9-bis[(3-hydroxypropyl)amino]benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetrone, DNA (5'-D(*DTP*DAP*DGP*DGP*DGP*DTP*DTP*DAP*DGP*DGP*DGP*DT)-3'), POTASSIUM ION, ...
Authors:Parkinson, G.N, Neidle, S.
Deposit date:2008-02-26
Release date:2008-09-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Topology conservation and loop flexibility in quadruplex-drug recognition: crystal structures of inter- and intramolecular telomeric DNA quadruplex-drug complexes
J.Mol.Biol., 381, 2008
8FP4
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BU of 8fp4 by Molmil
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 500mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na610)
Descriptor: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Nakagawa, T.
Deposit date:2023-01-04
Release date:2024-02-28
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FQF
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BU of 8fqf by Molmil
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 150mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na260)
Descriptor: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Nakagawa, T.
Deposit date:2023-01-06
Release date:2024-02-28
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.29 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FQ5
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BU of 8fq5 by Molmil
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Na110)
Descriptor: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-02-28
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.34 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FQG
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BU of 8fqg by Molmil
LBD conformation 1 (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 150mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na260)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-06
Release date:2024-02-28
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FQ8
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BU of 8fq8 by Molmil
LBD conformation 1 (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Na110)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-02-28
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FQE
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BU of 8fqe by Molmil
LBD conformation 2 (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 10mM CaCl2, 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Ca10)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-06
Release date:2024-02-28
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FQ2
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BU of 8fq2 by Molmil
LBD conformation 1 (LBDconf1) of GluA2 flip Q isoform N619K mutant of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg/N619K)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-02-28
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FQD
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BU of 8fqd by Molmil
LBD conformation 1 (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 10mM CaCl2, 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Ca10)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-06
Release date:2024-02-28
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FPS
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BU of 8fps by Molmil
GluA2 flip Q isoform N619K mutant of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg/N619K)
Descriptor: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-02-28
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.38 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FQ6
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BU of 8fq6 by Molmil
LBD of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 150mM CaCl2, 330uM CTZ, and 100mM L-glutamate (Open-Ca150)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-02-28
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FQB
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BU of 8fqb by Molmil
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 10mM CaCl2, 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Ca10)
Descriptor: CALCIUM ION, CHLORIDE ION, Glutamate receptor 2, ...
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-02-28
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.36 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FR0
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BU of 8fr0 by Molmil
LBD conformation 3 (LBDconf3) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 150mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na260)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-06
Release date:2024-02-28
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FQ3
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BU of 8fq3 by Molmil
LBD conformation 2 (LBDconf2) of GluA2 flip Q isoform N619K mutant of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg/N619K)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-02-28
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FQH
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BU of 8fqh by Molmil
LBD conformation 2 (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 150mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na260)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-06
Release date:2024-02-28
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FQ1
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BU of 8fq1 by Molmil
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 150mM CaCl2, 330uM CTZ, and 100mM L-glutamate (Open-Ca150)
Descriptor: CALCIUM ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-02-28
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (5.59 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FPY
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BU of 8fpy by Molmil
LBD conformation 2 (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 500mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na610)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-03-06
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FPV
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BU of 8fpv by Molmil
LBD conformation 1 (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 500mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na610)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-03-06
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FPZ
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BU of 8fpz by Molmil
LBD conformation 3 (LBDconf3) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 500mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na610)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-03-06
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FQA
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BU of 8fqa by Molmil
LBD conformation 2 (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Na110)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2
Authors:Nakagawa, T.
Deposit date:2023-01-05
Release date:2024-03-06
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
4OMJ
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BU of 4omj by Molmil
Crystal structure of SPF bound to 2,3-oxidosqualene
Descriptor: (3S)-2,2-dimethyl-3-[(3E,7E,11E,15E)-3,7,12,16,20-pentamethylhenicosa-3,7,11,15,19-pentaen-1-yl]oxirane, CHLORIDE ION, SEC14-like protein 2, ...
Authors:Christen, M, Marcaida, M.J, Lamprakis, C, Cascella, M, Stocker, A.
Deposit date:2014-01-27
Release date:2015-04-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights on cholesterol endosynthesis: Binding of squalene and 2,3-oxidosqualene to supernatant protein factor.
J.Struct.Biol., 190, 2015

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