4OMJ

Crystal structure of SPF bound to 2,3-oxidosqualene

Summary for 4OMJ

Entry DOI	10.2210/pdb4omj/pdb
Related	1O6U 1OLM 4OMK
Descriptor	SEC14-like protein 2, SULFATE ION, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	cholesterol synthesis, squalene, 2, 3-oxidosqualene, sec14-like, cral-trio domain, hydrophobic ligand transporter, transport protein
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: O76054
Total number of polymer chains	2
Total formula weight	65823.12
Authors	Christen, M.,Marcaida, M.J.,Lamprakis, C.,Cascella, M.,Stocker, A. (deposition date: 2014-01-27, release date: 2015-04-15, Last modification date: 2023-09-20)
Primary citation	Christen, M.,Marcaida, M.J.,Lamprakis, C.,Aeschimann, W.,Vaithilingam, J.,Schneider, P.,Hilbert, M.,Schneider, G.,Cascella, M.,Stocker, A. Structural insights on cholesterol endosynthesis: Binding of squalene and 2,3-oxidosqualene to supernatant protein factor. J.Struct.Biol., 190:261-270, 2015 Cited by PubMed: 25987292 DOI: 10.1016/j.jsb.2015.05.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation