Crystal structure of SPF bound to 2,3-oxidosqualene

Summary for 4OMJ

Related1OLM 1O6U 4OMK
DescriptorSEC14-like protein 2, SULFATE ION, CHLORIDE ION, ... (5 entities in total)
Functional Keywords2, cholesterol synthesis, squalene, 3-oxidosqualene, sec14-like, cral-trio domain, hydrophobic ligand transporter, transport protein
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm O76054
Total number of polymer chains2
Total molecular weight65823.12
Christen, M.,Marcaida, M.J.,Lamprakis, C.,Cascella, M.,Stocker, A. (deposition date: 2014-01-27, release date: 2015-04-15, Last modification date: 2015-06-24)
Primary citation
Christen, M.,Marcaida, M.J.,Lamprakis, C.,Aeschimann, W.,Vaithilingam, J.,Schneider, P.,Hilbert, M.,Schneider, G.,Cascella, M.,Stocker, A.
Structural insights on cholesterol endosynthesis: Binding of squalene and 2,3-oxidosqualene to supernatant protein factor.
J.Struct.Biol., 190:261-270, 2015
PubMed: 25987292 (PDB entries with the same primary citation)
DOI: 10.1016/j.jsb.2015.05.001
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.1813001.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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