4OMK

Crystal structure of SPF bound to squalene

Summary for 4OMK

Related1OLM 1O6U 4OMJ
DescriptorSEC14-like protein 2, SULFATE ION, CHLORIDE ION, ... (6 entities in total)
Functional Keywords2, cholesterol synthesis, squalene, 3-oxidosqualene, sec14-like, cral-trio domain, hydrophobic ligand transporter, transport protein
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm O76054
Total number of polymer chains2
Total molecular weight65567.08
Authors
Christen, M.,Marcaida, M.J.,Lamprakis, C.,Cascella, M.,Stocker, A. (deposition date: 2014-01-27, release date: 2015-04-15, Last modification date: 2015-06-24)
Primary citation
Christen, M.,Marcaida, M.J.,Lamprakis, C.,Aeschimann, W.,Vaithilingam, J.,Schneider, P.,Hilbert, M.,Schneider, G.,Cascella, M.,Stocker, A.
Structural insights on cholesterol endosynthesis: Binding of squalene and 2,3-oxidosqualene to supernatant protein factor.
J.Struct.Biol., 190:261-270, 2015
PubMed: 25987292 (PDB entries with the same primary citation)
DOI: 10.1016/j.jsb.2015.05.001
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.75 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.173300.6%2.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4omk
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Molmil generated image of 4omk
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Molmil generated image of 4omk
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More Biological unit images

Molmil generated image of 4omk
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Molmil generated image of 4omk
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Molmil generated image of 4omk
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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (4omk.pdb2.gz [101.32 KB])
Coordinate files for Biological unit (4omk.pdb1.gz [101.66 KB])