8FPV

LBD conformation 1 (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 500mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na610)

Summary for 8FPV

Entry DOI	10.2210/pdb8fpv/pdb
EMDB information	29359 29370
Descriptor	Glutamate receptor 2, GLUTAMIC ACID, CYCLOTHIAZIDE, ... (4 entities in total)
Functional Keywords	ionotropic glutamate receptor, ligand gated ion channel, ampa receptor, tarp gamma-2, transport protein
Biological source	Rattus norvegicus (Norway rat)
Total number of polymer chains	4
Total formula weight	400385.87
Authors	Nakagawa, T. (deposition date: 2023-01-05, release date: 2024-03-06, Last modification date: 2024-03-13)
Primary citation	Nakagawa, T.,Wang, X.T.,Miguez-Cabello, F.J.,Bowie, D. The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38409505 DOI: 10.1038/s41594-024-01228-3 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.08 Å)

Structure validation