8FQF
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 150mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na260)
Summary for 8FQF
| Entry DOI | 10.2210/pdb8fqf/pdb |
| EMDB information | 29360 29386 |
| Descriptor | Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit, CHLORIDE ION, ... (4 entities in total) |
| Functional Keywords | ionotropic glutamate receptor, ligand gated ion channel, ampa receptor, tarp gamma-2, transport protein |
| Biological source | Rattus norvegicus (Norway rat) More |
| Total number of polymer chains | 8 |
| Total formula weight | 546747.99 |
| Authors | Nakagawa, T. (deposition date: 2023-01-06, release date: 2024-02-28, Last modification date: 2024-05-01) |
| Primary citation | Nakagawa, T.,Wang, X.T.,Miguez-Cabello, F.J.,Bowie, D. The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31:688-700, 2024 Cited by PubMed: 38409505DOI: 10.1038/s41594-024-01228-3 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.29 Å) |
Structure validation
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