7TH0
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![BU of 7th0 by Molmil](/molmil-images/mine/7th0) | Escherichia coli RpnA-S | Descriptor: | Recombination-promoting nuclease RpnA | Authors: | Zhong, A, Hickman, A.B, Storz, G, Dyda, F. | Deposit date: | 2022-01-10 | Release date: | 2023-03-29 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Toxic antiphage defense proteins inhibited by intragenic antitoxin proteins. Proc.Natl.Acad.Sci.USA, 120, 2023
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4QNH
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![BU of 4qnh by Molmil](/molmil-images/mine/4qnh) | Calcium-calmodulin (T79D) complexed with the calmodulin binding domain from a small conductance potassium channel SK2-a | Descriptor: | CALCIUM ION, Calmodulin, SULFATE ION, ... | Authors: | Zhang, M, Pascal, J.M, Logothetis, D.E, Zhang, J.F. | Deposit date: | 2014-06-17 | Release date: | 2014-08-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Selective phosphorylation modulates the PIP2 sensitivity of the CaM-SK channel complex. Nat.Chem.Biol., 10, 2014
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3RLU
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![BU of 3rlu by Molmil](/molmil-images/mine/3rlu) | Crystal structure of the mutant K82A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP | Descriptor: | 6-HYDROXYURIDINE-5'-PHOSPHATE, GLYCEROL, Orotidine 5'-phosphate decarboxylase | Authors: | Fedorov, A.A, Fedorov, E.V, Desai, B, Gerlt, J.A, Almo, S.C. | Deposit date: | 2011-04-20 | Release date: | 2012-04-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry, 51, 2012
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5O3Q
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![BU of 5o3q by Molmil](/molmil-images/mine/5o3q) | Carbon regulatory PII-like protein SbtB from Synechocystis sp. 6803 in complex with cyclic AMP (cAMP) | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, BICARBONATE ION, Membrane-associated protein slr1513 | Authors: | Selim, K.A, Albrecht, R, Forchhammer, K, Hartmann, M.D. | Deposit date: | 2017-05-24 | Release date: | 2018-05-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | PII-like signaling protein SbtB links cAMP sensing with cyanobacterial inorganic carbon response. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6PEE
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![BU of 6pee by Molmil](/molmil-images/mine/6pee) | |
2CFB
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![BU of 2cfb by Molmil](/molmil-images/mine/2cfb) | Glutamate-1-semialdehyde 2,1-Aminomutase from Thermosynechococcus elongatus | Descriptor: | (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE | Authors: | Schulze, J.O, Schubert, W.-D, Moser, J, Jahn, D, Heinz, D.W. | Deposit date: | 2006-02-17 | Release date: | 2006-03-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Evolutionary Relationship between Initial Enzymes of Tetrapyrrole Biosynthesis J.Mol.Biol., 358, 2006
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7O45
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![BU of 7o45 by Molmil](/molmil-images/mine/7o45) | Crystal structure of ADD domain of the human DNMT3B methyltransferase | Descriptor: | BROMIDE ION, Isoform 6 of DNA (cytosine-5)-methyltransferase 3B, ZINC ION | Authors: | Boyko, K.M, Nikolaeva, A.Y, Bonchuk, A.N, Georgiev, P.G, Popov, V.O. | Deposit date: | 2021-04-05 | Release date: | 2022-04-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the DNMT3B ADD domain suggests the absence of a DNMT3A-like autoinhibitory mechanism. Biochem.Biophys.Res.Commun., 619, 2022
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6PIF
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![BU of 6pif by Molmil](/molmil-images/mine/6pif) | V. cholerae TniQ-Cascade complex, open conformation | Descriptor: | Cas7, type I-F CRISPR-associated protein, TniQ monomer 1, ... | Authors: | Halpin-Healy, T, Klompe, S, Sternberg, S.H. | Deposit date: | 2019-06-26 | Release date: | 2019-10-02 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system. Nature, 577, 2020
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5OHN
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![BU of 5ohn by Molmil](/molmil-images/mine/5ohn) | |
7TFF
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![BU of 7tff by Molmil](/molmil-images/mine/7tff) | Crystal structure of human platelet phosphofructokinase-1 mutant- D564N | Descriptor: | ATP-dependent 6-phosphofructokinase, platelet type, PHOSPHATE ION, ... | Authors: | Hansen, H, Webb, B.A, Robart, A.R, Narayanasami, S. | Deposit date: | 2022-01-06 | Release date: | 2023-07-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Cancer-associated somatic mutations in human phosphofructokinase-1 reveal a critical electrostatic interaction for allosteric regulation of enzyme activity. Biochem.J., 480, 2023
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3P3W
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![BU of 3p3w by Molmil](/molmil-images/mine/3p3w) | |
4QTR
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![BU of 4qtr by Molmil](/molmil-images/mine/4qtr) | Computational design of co-assembling protein-DNA nanowires | Descriptor: | DNA (5'-D(P*CP*GP*GP*AP*AP*AP*TP*TP*AP*AP*AP*TP*TP*AP*CP*A)-3'), DNA (5'-D(P*GP*TP*GP*TP*AP*AP*TP*TP*TP*AP*AP*TP*TP*TP*CP*C)-3'), dualENH | Authors: | Mou, Y, Mayo, S.L. | Deposit date: | 2014-07-08 | Release date: | 2015-07-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Computational design of co-assembling protein-DNA nanowires. Nature, 525, 2015
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5OMM
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![BU of 5omm by Molmil](/molmil-images/mine/5omm) | |
3P61
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![BU of 3p61 by Molmil](/molmil-images/mine/3p61) | Crystal structure of the mutant R160A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP | Descriptor: | 6-HYDROXYURIDINE-5'-PHOSPHATE, Orotidine 5'-monophosphate decarboxylase | Authors: | Fedorov, A.A, Fedorov, E.V, Wood, B.M, Gerlt, J.A, Almo, S.C. | Deposit date: | 2010-10-11 | Release date: | 2011-09-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.396 Å) | Cite: | Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry, 51, 2012
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4R08
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![BU of 4r08 by Molmil](/molmil-images/mine/4r08) | Crystal structure of human TLR8 in complex with ssRNA40 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3'-O-[(R)-{[(2R,3aR,4R,6R,6aR)-6-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-2-hydroxy-2-oxidotetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-4-yl]methoxy}(hydroxy)phosphoryl]uridine 5'-(dihydrogen phosphate), ... | Authors: | Tanji, H, Ohto, U, Shimizu, T. | Deposit date: | 2014-07-30 | Release date: | 2015-01-14 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Toll-like receptor 8 senses degradation products of single-stranded RNA. Nat.Struct.Mol.Biol., 22, 2015
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6PD4
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![BU of 6pd4 by Molmil](/molmil-images/mine/6pd4) | Crystal Structure of Hendra Virus Attachment G Glycoprotein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Attachment glycoprotein, ... | Authors: | Xu, K, Nikolov, D.B. | Deposit date: | 2019-06-18 | Release date: | 2019-11-27 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | New insights into the Hendra virus attachment and entry process from structures of the virus G glycoprotein and its complex with Ephrin-B2. PLoS ONE, 7, 2012
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4QUZ
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![BU of 4quz by Molmil](/molmil-images/mine/4quz) | |
4QVA
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![BU of 4qva by Molmil](/molmil-images/mine/4qva) | |
3P5Z
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![BU of 3p5z by Molmil](/molmil-images/mine/3p5z) | Crystal structure of the mutant T159S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP | Descriptor: | 6-HYDROXYURIDINE-5'-PHOSPHATE, GLYCEROL, N-PROPANOL, ... | Authors: | Fedorov, A.A, Fedorov, E.V, Wood, B.M, Gerlt, J.A, Almo, S.C. | Deposit date: | 2010-10-11 | Release date: | 2011-09-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry, 51, 2012
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6POE
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![BU of 6poe by Molmil](/molmil-images/mine/6poe) | Structure of ACLY in complex with CoA | Descriptor: | ATP-citrate synthase, COENZYME A | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2019-07-03 | Release date: | 2019-12-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Molecular basis for acetyl-CoA production by ATP-citrate lyase. Nat.Struct.Mol.Biol., 27, 2020
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6Y4M
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![BU of 6y4m by Molmil](/molmil-images/mine/6y4m) | Structure of Tubulin Tyrosine Ligase in Complex with Tb111 | Descriptor: | (2~{R})-1-methylpiperidine-2-carboxylic acid, (2~{S},4~{R})-4-azanyl-2-methyl-5-phenyl-pentanoic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | Authors: | Gavrilyuk, J, Nocek, B, Rigol, S, Nicolaou, K.C, Stoll, V. | Deposit date: | 2020-02-21 | Release date: | 2021-03-31 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (3.34 Å) | Cite: | Design, Synthesis, and Biological Evaluation of Tubulysin Analogues, Linker-Drugs, and Antibody-Drug Conjugates, Insights into Structure-Activity Relationships, and Tubulysin-Tubulin Binding Derived from X-ray Crystallographic Analysis. J.Org.Chem., 86, 2021
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3SJ3
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![BU of 3sj3 by Molmil](/molmil-images/mine/3sj3) | Crystal structure of the mutant R160A.Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP | Descriptor: | 6-HYDROXYURIDINE-5'-PHOSPHATE, Orotidine 5'-phosphate decarboxylase | Authors: | Fedorov, A.A, Fedorov, E.V, Desai, B, Gerlt, J.A, Almo, S.C. | Deposit date: | 2011-06-20 | Release date: | 2011-06-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.26 Å) | Cite: | Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry, 51, 2012
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7QH7
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![BU of 7qh7 by Molmil](/molmil-images/mine/7qh7) | Cryo-EM structure of the human mtLSU assembly intermediate upon MRM2 depletion - class 4 | Descriptor: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | Authors: | Rebelo-Guiomar, P, Pellegrino, S, Dent, K.C, Warren, A.J, Minczuk, M. | Deposit date: | 2021-12-10 | Release date: | 2022-05-18 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit. Nat Commun, 13, 2022
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1PI6
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![BU of 1pi6 by Molmil](/molmil-images/mine/1pi6) | YEAST ACTIN INTERACTING PROTEIN 1 (Aip1), ORTHORHOMBIC CRYSTAL FORM | Descriptor: | Actin interacting protein 1, ZINC ION | Authors: | Voegtli, W.C, Madrona, A.Y, Wilson, D.K. | Deposit date: | 2003-05-29 | Release date: | 2003-07-15 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The structure of Aip1p, a WD repeat protein that regulates Cofilin-mediated actin depolymerization. J.Biol.Chem., 278, 2003
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5OW6
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![BU of 5ow6 by Molmil](/molmil-images/mine/5ow6) | CryoEM structure of recombinant CMV particles with Tetanus-epitope | Descriptor: | Capsid protein, VP2, VP3, ... | Authors: | Kotecha, A, Stuart, D.I, Backmann, M. | Deposit date: | 2017-08-30 | Release date: | 2017-09-13 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Incorporation of tetanus-epitope into virus-like particles achieves vaccine responses even in older recipients in models of psoriasis, Alzheimer's and cat allergy. NPJ Vaccines, 2, 2017
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