Computational design of co-assembling protein-DNA nanowires

Summary for 4QTR

DescriptordualENH, DNA (5'-D(P*GP*TP*GP*TP*AP*AP*TP*TP*TP*AP*AP*TP*TP*TP*CP*C)-3'), DNA (5'-D(P*CP*GP*GP*AP*AP*AP*TP*TP*AP*AP*AP*TP*TP*AP*CP*A)-3') (3 entities in total)
Functional Keywordshelix-turn-helix, dna-binding protein, double-stranded dna, de novo design-dna complex, de novo design/dna
Biological sourceDrosophila melanogaster
Total number of polymer chains8
Total molecular weight54320.5
Mou, Y.,Mayo, S.L. (deposition date: 2014-07-08, release date: 2015-07-29, Last modification date: 2015-09-30)
Primary citation
Mou, Y.,Yu, J.Y.,Wannier, T.M.,Guo, C.L.,Mayo, S.L.
Computational design of co-assembling protein-DNA nanowires.
Nature, 525:230-233, 2015
PubMed: 26331548 (PDB entries with the same primary citation)
DOI: 10.1038/nature14874
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.32613001.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report