7QH7

Cryo-EM structure of the human mtLSU assembly intermediate upon MRM2 depletion - class 4

Summary for 7QH7

• Entry DOI: 10.2210/pdb7qh7/pdb
• EMDB information: 13962 13963 13965 13966 13967
• Descriptor: 39S ribosomal protein L2, mitochondrial, 39S ribosomal protein L17, mitochondrial, 39S ribosomal protein L18, mitochondrial, ... (52 entities in total)
• Functional Keywords: mitochondria, ribosome, assembly, methyltransferase, mrm2, rna modification
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 49
• Total formula weight: 1248835.72

Authors

Rebelo-Guiomar, P.,Pellegrino, S.,Dent, K.C.,Warren, A.J.,Minczuk, M. (deposition date: 2021-12-10, release date: 2022-05-18)

• Primary citation: Rebelo-Guiomar, P.,Pellegrino, S.,Dent, K.C.,Sas-Chen, A.,Miller-Fleming, L.,Garone, C.,Van Haute, L.,Rogan, J.F.,Dinan, A.,Firth, A.E.,Andrews, B.,Whitworth, A.J.,Schwartz, S.,Warren, A.J.,Minczuk, M.; A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit.; Nat Commun, 13:929-929, 2022; PubMed: 35177605; DOI: 10.1038/s41467-022-28503-5

Experimental method

ELECTRON MICROSCOPY (2.89 Å)