7O45

Crystal structure of ADD domain of the human DNMT3B methyltransferase

Summary for 7O45

Entry DOI	10.2210/pdb7o45/pdb
Descriptor	Isoform 6 of DNA (cytosine-5)-methyltransferase 3B, ZINC ION, BROMIDE ION, ... (4 entities in total)
Functional Keywords	methyltransferase 3b, dna methylation, dnmt3b, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	67251.37
Authors	Boyko, K.M.,Nikolaeva, A.Y.,Bonchuk, A.N.,Georgiev, P.G.,Popov, V.O. (deposition date: 2021-04-05, release date: 2022-04-13, Last modification date: 2024-01-31)
Primary citation	Boyko, K.,Arkova, O.,Nikolaeva, A.,Popov, V.O.,Georgiev, P.,Bonchuk, A. Structure of the DNMT3B ADD domain suggests the absence of a DNMT3A-like autoinhibitory mechanism. Biochem.Biophys.Res.Commun., 619:124-129, 2022 Cited by PubMed: 35760008 DOI: 10.1016/j.bbrc.2022.06.036 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation